维持性血液透析患者中与肝炎相关的神经病变
Neuropathy associated with hepatitis in patients maintained on haemodialysis.
作者信息
Davison A M, Williams I R, Mawdsley C, Robson J S
出版信息
Br Med J. 1972 Feb 12;1(5797):409-11. doi: 10.1136/bmj.1.5797.409.
During a study of peripheral nerve function in chronic renal failure, 11 patients who were being treated by chronic intermittent haemodialysis developed serum hepatitis. Before the infection there was a trend towards improvement in nerve conduction velocities. A pronounced deterioration in the conduction velocities in motor fibres of peripheral nerves occurred in association with hepatitis. In the months after recovery from the infection there was again a trend towards improvement in conduction velocities. We suggest that this reflects the occurrence of a peripheral neuropathy which is at least in part demyelinating. The neuropathy is related to the serum hepatitis, but its pathogenesis is indeterminate.
在一项关于慢性肾功能衰竭患者周围神经功能的研究中，11名接受慢性间歇性血液透析治疗的患者发生了血清型肝炎。感染前神经传导速度有改善的趋势。肝炎发作时，周围神经运动纤维的传导速度显著恶化。感染恢复后的几个月里，传导速度再次呈现改善趋势。我们认为，这反映了一种至少部分为脱髓鞘性的周围神经病变的发生。这种神经病变与血清型肝炎有关，但其发病机制尚不清楚。
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