缺乏诱导核酸内切酶II能力的噬菌体T4突变体的基因定位
Genetic location of a mutant of bacteriophage T4 deficient in the ability to induce endonuclease II.
作者信息
Ray P, Sinha N K, Warner H R, Snustad D P
出版信息
J Virol. 1972 Jan;9(1):184-6. doi: 10.1128/JVI.9.1.184-186.1972.
Abstract
Reciprocal three-factor crosses and the use of a partial revertant of a putative ribonucleotide reductase mutant of Escherichia coli B/5 as indicator have made it possible to map denA (deficient in endonuclease II) between nrd-11 (ribonucleotide reductase gene B) and amM69 (gene 63) on the bacteriophage T4 chromosome.
摘要
通过相互三因子杂交以及使用大肠杆菌B/5假定的核糖核苷酸还原酶突变体的部分回复突变体作为指示物，得以将denA（核酸内切酶II缺陷型）定位在噬菌体T4染色体上的nrd-11（核糖核苷酸还原酶基因B）和amM69（基因63）之间。
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