Latner A L, Longstaff E, Lunn J M
Br J Cancer. 1971 Sep;25(3):568-73. doi: 10.1038/bjc.1971.72.
A technique was developed to study the invasion of cells into mouse kidney cortex in the presence of crude rat liver histone at a medium concentration of 100 μg./ml. A marked increase in the invasiveness of normal cells occurred in the presence of histone. Possible explanations of this phenomenon are discussed. The invasiveness was compared with that of cells previously transformed with polyoma virus.
开发了一种技术，用于研究在浓度为100μg/ml的粗制大鼠肝脏组蛋白存在下细胞对小鼠肾皮质的侵袭。在组蛋白存在的情况下，正常细胞的侵袭性显著增加。讨论了这种现象可能的解释。将这种侵袭性与先前用多瘤病毒转化的细胞的侵袭性进行了比较。
