Nielsen N V, Lund F S
Acta Neurol Scand. 1979 Jan;59(1):15-22. doi: 10.1111/j.1600-0404.1979.tb02906.x.
In a controlled study, corneal sensitivity, vibratory perception of the left index finger and great toe and achilles tendon reflex were examined in 100 diabetes patients and 100 controls. The result showed significantly reduced corneal sensitivity, vibratory perception and increased number of areflexi in the diabetic group. Furthermore, the decrease of corneal sensitivity, vibratory perception and presence of areflexi correlated well to one another and to age, duration of D. M. above 15 years and diabetic retinopathy. Significant intercorrelations suggest that a reduced corneal touch threshold forms part of a polyneuropathy in diabetes. A corneal hypesthesia cannot be considered a valuable index in screening a population for diabetes as previously has been suggested.
在一项对照研究中，对100例糖尿病患者和100例对照者进行了角膜敏感性、左手食指和大脚趾的振动觉以及跟腱反射检查。结果显示，糖尿病组的角膜敏感性、振动觉显著降低，无反射者数量增加。此外，角膜敏感性降低、振动觉降低和无反射现象之间以及与年龄、糖尿病病程超过15年和糖尿病视网膜病变之间均存在良好的相关性。显著的相互关系表明，角膜触觉阈值降低是糖尿病多发性神经病变的一部分。角膜感觉减退不能像之前所认为的那样，被视为筛查人群糖尿病的有价值指标。
