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猫白血病病毒感染的细胞病变试验。

Cytopathogenic test for feline leukemia virus infections.

作者信息

Rangan S R, Wong M C, Moyer P P, Jensen E M

出版信息

Appl Microbiol. 1972 Mar;23(3):628-36. doi: 10.1128/am.23.3.628-636.1972.

DOI:10.1128/am.23.3.628-636.1972
PMID:4336663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC380398/
Abstract

A mixed culture cytopathogenic effect with the development of multinucleated giant cells in feline leukemia virus-infected cultures after cocultivation with XC cells is described. This cytopathogenic effect has been utilized as a convenient visual marker for the detection and assay of feline leukemia virus in feline and canine embryo fibroblasts as well as in a canine tumor cell line, M-132-1. Comparison of the cytopathogenic reaction in the three cell lines indicates that the reaction is more rapid and pronounced in M-132-1 cells than in the embryo fibroblast cultures.

摘要

本文描述了猫白血病病毒感染的培养物与XC细胞共培养后出现的多核巨细胞发育的混合培养细胞病变效应。这种细胞病变效应已被用作一种方便的视觉标记，用于检测和测定猫和犬胚胎成纤维细胞以及犬肿瘤细胞系M-132-1中的猫白血病病毒。三种细胞系中细胞病变反应的比较表明，M-132-1细胞中的反应比胚胎成纤维细胞培养物中的反应更迅速、更明显。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30dc/380398/5a1e53ac3bb1/applmicro00044-0215-a.jpg

相似文献

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本文引用的文献

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Presence of chicken tumour virus in the sarcoma of the adult rat inoculated after birth with Rous sarcoma tissue.出生后接种劳斯肉瘤组织的成年大鼠肉瘤中鸡肿瘤病毒的存在情况。
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Complement-fixation test for feline leukemia and sarcoma viruses (the COCAL test).
Virology. 1971 Apr;44(1):137-45. doi: 10.1016/0042-6822(71)90160-7.
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Detection and assay of feline leukemia virus (FeLV) by a mixed-culture cytopathogenicity method.采用混合培养细胞病变法检测和测定猫白血病病毒（FeLV）
Virology. 1972 Jan;47(1):247-50. doi: 10.1016/0042-6822(72)90258-9.
7
Analysis of the fusion of XC cells induced by homogenates of murine leukemia virus-infected cells and by purified murine leukemia virus.对由鼠白血病病毒感染细胞的匀浆和纯化的鼠白血病病毒诱导的XC细胞融合的分析。
J Virol. 1971 Jun;7(6):753-8. doi: 10.1128/JVI.7.6.753-758.1971.
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Mixed culture cytopathogenicity: a new test for growth of murine leukemia viruses in tissue culture.混合培养细胞致病性：一种检测小鼠白血病病毒在组织培养中生长情况的新试验。
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A fluorescent antibody technique for the detection of the group-specific antigen of feline leukemia virus in infected tissue-culture cells.
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Plaque assay techniques for murine leukemia viruses.小鼠白血病病毒的噬斑测定技术
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