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Ether-lipids, -glycerol phosphate dehydrogenase, and growth rate in tumors and cultured cells.

作者信息

Howard B V, Morris H P, Bailey J M

出版信息

Cancer Res. 1972 Jul;32(7):1533-8.

PMID:4337833
Abstract
摘要

相似文献

1
Ether-lipids, -glycerol phosphate dehydrogenase, and growth rate in tumors and cultured cells.醚脂、甘油磷酸脱氢酶与肿瘤及培养细胞中的生长速率
Cancer Res. 1972 Jul;32(7):1533-8.
2
Glycerol-3-phosphate dehydrogenase is induced by glucocorticoids in hepatocytes and hepatoma cells in vitro.在体外,甘油-3-磷酸脱氢酶可被糖皮质激素诱导于肝细胞和肝癌细胞中。
J Cell Physiol. 1983 Feb;114(2):203-8. doi: 10.1002/jcp.1041140209.
3
Control of the adenylate charge in Novikoff ascites cells.诺维科夫腹水癌细胞中腺苷酸能荷的调控
Cancer Res. 1973 Jan;33(1):57-64.
4
Control of the adenylate charge in the Morris "minimal-deviation" hepatomas.对莫里斯“最小偏差”肝癌中腺苷酸能荷的控制
Cancer Res. 1973 Jan;33(1):51-6.
5
Proportional activities of glycerol kinase and glycerol 3-phosphate dehydrogenase in rat hepatomas.大鼠肝癌中甘油激酶和3-磷酸甘油脱氢酶的比例活性。
Biochem J. 1975 Jun;148(3):545-50. doi: 10.1042/bj1480545.
6
Rat liver glycerolphosphate dehydrogenases: activity changes and induction by thyroid hormone of the mitochondrial enzyme in hepatomas and in precancerous and growing liver.
Acta Biol Med Ger. 1971;26(6):1131-40.
7
Glycerol utilization and its regulation in mammals.
Annu Rev Biochem. 1977;46:765-95. doi: 10.1146/annurev.bi.46.070177.004001.
8
Factors affecting anaerobic glycolysis in mouse and rat liver and in Morris rat hepatomas.
J Natl Cancer Inst. 1968 Aug;41(2):267-86.
9
Mouse lacking NAD+-linked glycerol phosphate dehydrogenase has normal pancreatic beta cell function but abnormal metabolite pattern in skeletal muscle.缺乏烟酰胺腺嘌呤二核苷酸(NAD⁺)连接的磷酸甘油脱氢酶的小鼠具有正常的胰腺β细胞功能,但骨骼肌中的代谢物模式异常。
Arch Biochem Biophys. 2000 Dec 1;384(1):143-53. doi: 10.1006/abbi.2000.2107.
10
Evidence for bile acid synthesis by transplantable hepatomas.可移植性肝癌合成胆汁酸的证据。
Cancer Res. 1974 Jul;34(7):1688-93.

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敲低 HSDL2 通过下调 AKT2 表达抑制肺腺癌进展。
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Lentivirus-mediated overexpression of HSDL2 suppresses cell proliferation and induces apoptosis in cholangiocarcinoma.慢病毒介导的HSDL2过表达抑制胆管癌细胞增殖并诱导其凋亡。
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Lentivirus-mediated silencing of HSDL2 suppresses cell proliferation in human gliomas.慢病毒介导的HSDL2沉默抑制人胶质瘤细胞增殖。
Tumour Biol. 2016 Nov;37(11):15065-15077. doi: 10.1007/s13277-016-5402-6. Epub 2016 Sep 22.
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Discovery of Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anti-Cancer Agents.发现醚脂生成酶AGPS的抑制剂作为抗癌药物
ACS Chem Biol. 2015 Nov 20;10(11):2589-97. doi: 10.1021/acschembio.5b00466. Epub 2015 Sep 4.
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Targeting the plasma membrane of neoplastic cells through alkylation: a novel approach to cancer chemotherapy.通过烷基化作用靶向肿瘤细胞的质膜:癌症化疗的一种新方法。
Invest New Drugs. 2015 Aug;33(4):992-1001. doi: 10.1007/s10637-015-0263-1. Epub 2015 Jun 23.
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Peroxisomes: a nexus for lipid metabolism and cellular signaling.过氧化物酶体:脂质代谢与细胞信号传导的枢纽
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10
Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity.醚脂生成酶 AGPS 改变了结构脂质和信号脂质的平衡,为癌症的发病机制提供燃料。
Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14912-7. doi: 10.1073/pnas.1310894110. Epub 2013 Aug 26.