酶原中活性位点的预先存在，胰蛋白酶原与碱性胰腺胰蛋白酶抑制剂（库尼茨）的相互作用。 - Suppr

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超能文献

Pre-existence of the active site in zymogens, the interaction of trypsinogen with the basic pancreatic trypsin inhibitor (Kunitz).

作者信息

Vincent J P, Lazdunski M

出版信息

FEBS Lett. 1976 Apr 1;63(2):240-4. doi: 10.1016/0014-5793(76)80103-2.

DOI:10.1016/0014-5793(76)80103-2

PMID:4338

Abstract

摘要

相似文献

Pre-existence of the active site in zymogens, the interaction of trypsinogen with the basic pancreatic trypsin inhibitor (Kunitz).酶原中活性位点的预先存在，胰蛋白酶原与碱性胰腺胰蛋白酶抑制剂（库尼茨）的相互作用。

FEBS Lett. 1976 Apr 1;63(2):240-4. doi: 10.1016/0014-5793(76)80103-2.

Complex formation of guanidinated bovine trypsin inhibitor (Kunitz) with trypsin, chymotrypsin and trypsinogen as studied by the spin-label technique.用自旋标记技术研究胍基化牛胰蛋白酶抑制剂（库尼兹）与胰蛋白酶、胰凝乳蛋白酶和胰蛋白酶原的复合物形成。

FEBS Lett. 1982 Apr 5;140(1):53-7. doi: 10.1016/0014-5793(82)80519-x.

Active site in zymogens. Proton magnetic resonance pH titration curves of histidine-57 in porcine and bovine trypsinogens and in their complexes with bovine pancreatic trypsin inhibitor (Kunitz).酶原中的活性位点。猪和牛胰蛋白酶原及其与牛胰蛋白酶抑制剂（库尼茨）复合物中组氨酸-57的质子磁共振pH滴定曲线。

Biochemistry. 1978 Oct 31;17(22):4640-7. doi: 10.1021/bi00615a009.

Kinetics of the interaction of bovine pancreatic trypsin inhibitor (Kunitz) with alpha-chymotrypsin.牛胰蛋白酶抑制剂（库尼兹）与α-糜蛋白酶相互作用的动力学

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Comparison of the interactions of soya bean protease inhibitors with rat pancreatic enzymes and human trypsin.大豆蛋白酶抑制剂与大鼠胰腺酶及人胰蛋白酶相互作用的比较。

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Interaction with DNA of the acetylated and non-acetylated polyvalent basic trypsin inhibitor of the Kunitz type.

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The two human trypsinogens. Evidence of complex formation with basic pancreatic trypsin inhibitor-proteolytic activity.两种人胰蛋白酶原。与碱性胰腺胰蛋白酶抑制剂形成复合物及蛋白水解活性的证据。

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Replacement of lysine by arginine, phenylalanine and tryptophan in the reactive site of the bovine trypsin-kallikrein inhibitor (Kunitz) and change of the inhibitory properties.牛胰蛋白酶-激肽释放酶抑制剂（Kunitz）活性位点中赖氨酸被精氨酸、苯丙氨酸和色氨酸取代及其抑制特性的改变。

Eur J Biochem. 1976 Jan 15;61(2):453-63. doi: 10.1111/j.1432-1033.1976.tb10039.x.

Effect of dietary raw soybean and soybean trypsin inhibitor on trypsin and chymotrypsin activities in the pancreas and in small intestinal juice of growing swine.日粮生大豆及大豆胰蛋白酶抑制剂对生长猪胰腺和小肠液中胰蛋白酶及糜蛋白酶活性的影响

J Nutr. 1977 Jan;107(1):156-65. doi: 10.1093/jn/107.1.156.

[Bimolecular protein-protein interactions in microcapsules].[微胶囊中的双分子蛋白质-蛋白质相互作用]

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Protein flexibility, not disorder, is intrinsic to molecular recognition.蛋白质的灵活性而非无序性是分子识别的内在特性。

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Allosteric peptide activators of pro-hepatocyte growth factor stimulate Met signaling.变构肽激活物促进原肝生长因子刺激 Met 信号。

J Biol Chem. 2010 Dec 17;285(51):40362-72. doi: 10.1074/jbc.M110.179721. Epub 2010 Oct 11.

Effect of ethylene glycol and polyethylene glycol on the acid-unfolded state of trypsinogen.乙二醇和聚乙二醇对胰蛋白酶原酸变性状态的影响。

J Protein Chem. 2003 Nov;22(7-8):677-82. doi: 10.1023/b:jopc.0000008733.93463.ed.

Catalytic and ligand binding properties of bovine trypsinogen and its complex with the effector dipeptide Ile-Val. A comparative study.牛胰蛋白酶原及其与效应二肽异亮氨酸-缬氨酸复合物的催化和配体结合特性。一项比较研究。

Mol Cell Biochem. 1984;60(2):163-81. doi: 10.1007/BF00222487.

Benzamidine as a spectroscopic probe for the primary specificity subsite of trypsin-like serine proteinases. A case for BPTI binding to bovine beta-trypsin.苯甲脒作为类胰蛋白酶丝氨酸蛋白酶一级特异性亚位点的光谱探针。关于抑肽酶与牛β-胰蛋白酶结合的一个实例。

Mol Cell Biochem. 1984 Sep;64(2):139-44. doi: 10.1007/BF00224770.

Studies on ram acrosin. Activation of proacrosin accompanying the isolation of acrosin from spermatozoa, and purification of the enzyme by affinity chromatography.公羊顶体蛋白酶的研究。从精子中分离顶体蛋白酶时前顶体蛋白酶的激活，以及通过亲和层析法对该酶的纯化。

Biochem J. 1978 Oct 1;175(1):227-38. doi: 10.1042/bj1750227.

[Activation, activity and inhibition of bovine trypsin].

Naturwissenschaften. 1979 May;66(5):251-8. doi: 10.1007/BF00571605.

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