Papp J P
Am J Gastroenterol. 1979 Feb;71(2):154-7.
Thirty patients were studied prospectively in evaluating the Nissen (28) and Belsey (2) fundoplication manometrically using the Kronsberg probe and Honeywell recorder. Twenty-eight patients in the Nissen fundoplication group had abnormally low LESP preoperatively and normal postoperative for one year with an average increase of 9 mm. Hg. They became asymptomatic and their esophageal mucosa became normal and remained normal endoscopically for three years. The only failures were two patients treated with the Belsey fundoplication. The gas bloat syndrome occurred in two patients and was relieved by esophageal dilatation. The Nissen fundoplication should be highly recommended as the surgical procedure of choice in the treatment of reflux esophagitis not responding to medical program.
前瞻性地研究了30例患者,使用克朗斯贝格探头和霍尼韦尔记录仪通过测压法评估尼森(28例)和贝尔西(2例)胃底折叠术。尼森胃底折叠术组的28例患者术前下食管括约肌压力(LESP)异常低,术后一年内恢复正常,平均升高9毫米汞柱。他们症状消失,食管黏膜恢复正常,并且在内镜检查下三年内保持正常。仅有的失败病例是2例行贝尔西胃底折叠术的患者。2例患者出现气胀综合征,经食管扩张后缓解。对于药物治疗无效的反流性食管炎,强烈推荐尼森胃底折叠术作为首选手术方式。