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用于控制白纹伊蚊的雄性连锁易位有效性的计算机模拟

Computer simulation of the effectiveness of male-linked translocations for the control of Anopheles albimanus Wiedemann.

作者信息

Seawright J A, Haile D G, Rabbani M G, Weidhaas D E

出版信息

Am J Trop Med Hyg. 1979 Jan;28(1):155-60. doi: 10.4269/ajtmh.1979.28.155.

DOI:10.4269/ajtmh.1979.28.155
PMID:434306
Abstract

A deterministic simulation model was used to establish the potential value of releasing male-linked translocation heterozygotes as a control measure for Anopheles albimanus Wiedemann. Theoretical population reductions exceeding 90% were obtained within 90 and 120 days after releases at initial ratios of 5 translocation males (TM): 1 normal male (NM) and 1 TM: 1 NM, respectively. Additional simulations emphasized the importance of the need for a method that would eliminate females from the release material. Releases containing 15% females were less effective than those with none. When a malaria subroutine was included in the model, the calculations showed that all the theoretical releases greatly reduced the number of malaria-infective females and therefore would have a profound effect on transmission of the disease. The number of malaria-infective females present was eliminated completely when only translocation males were released; however, a small number were present when the releases contained 15% females. Male-linked translocation males required longer periods of time to bring about population control than males that were completely sterile.

摘要

使用确定性模拟模型来确定释放雄性连锁易位杂合子作为白纹伊蚊控制措施的潜在价值。在分别以5个易位雄蚊(TM):1个正常雄蚊(NM)和1个TM:1个NM的初始比例释放后90天和120天内,理论种群减少超过90%。额外的模拟强调了需要一种从释放材料中消除雌蚊的方法的重要性。含有15%雌蚊的释放不如不含雌蚊的释放有效。当模型中包含疟疾子程序时,计算表明所有理论释放都大大减少了感染疟疾的雌蚊数量,因此对疾病传播将产生深远影响。仅释放易位雄蚊时,存在的感染疟疾的雌蚊数量被完全消除;然而,当释放中含有15%雌蚊时,仍有少量存在。与完全不育的雄蚊相比,雄性连锁易位雄蚊实现种群控制需要更长时间。

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