Ascorbate-dependent differences in the hydroxylation of proline and lysine in collagen synthesized by 3T6 fibroblasts in culture.
作者信息
Bates C J, Prynne C J, Levene C I
出版信息
Biochim Biophys Acta. 1972 Oct 31;278(3):610-6. doi: 10.1016/0005-2795(72)90025-6.
PMID:4343675
Abstract
摘要
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Ascorbic Acid and gene expression: another example of regulation of gene expression by small molecules?抗坏血酸与基因表达：小分子调控基因表达的又一个例证？
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Failure of highly purified lysyl hydroxylase to hydroxylate lysyl residues in the non-helical regions of collagen.高纯度赖氨酰羟化酶无法使胶原蛋白非螺旋区域的赖氨酰残基发生羟基化。
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Abnormal properties of collagen lysyl hydroxylase from skin fibroblasts of siblings with hydroxylysine-deficient collagen.来自患有羟赖氨酸缺乏型胶原蛋白的同胞皮肤成纤维细胞的胶原蛋白赖氨酰羟化酶的异常特性。
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