用于治疗尿崩症的非激素类药物。
Non-hormonal drugs for the treatment of diabetes insipidus.
作者信息
Nawar T, Genest J
出版信息
Can Med Assoc J. 1972 Dec 23;107(12):1225-6 passim.
Abstract
Patients with diabetes insipidus may be successfully controlled with drugs other than vasopressin. These have the advantage of being effective when administered orally. The most important are the diuretics and the hypoglycemic agent chlorpropamide. The mode of action, indications and side effects of these drugs are reviewed. A third potentially useful agent is clofibrate. Recent experience with this drug has been described but more observations are needed before its possible role in the management of diabetes insipidus can be established.
摘要
尿崩症患者可用血管加压素以外的药物成功控制。这些药物的优点是口服有效。最重要的是利尿剂和降血糖药氯磺丙脲。本文综述了这些药物的作用方式、适应证和副作用。第三种可能有用的药物是氯贝丁酯。已经描述了关于这种药物的近期经验，但在确定其在尿崩症治疗中可能的作用之前，还需要更多的观察。
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Non-hormonal drugs for the treatment of diabetes insipidus.用于治疗尿崩症的非激素类药物。
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引用本文的文献
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Familial ADH-responsive diabetes insipidus: response to thiazides and chlorpropamide.家族性抗利尿激素反应性尿崩症：对噻嗪类药物和氯磺丙脲的反应。
Can Med Assoc J. 1973 Oct 6;109(7):594-7.
2
Electrolyte disorders in the elderly.
Drugs Aging. 1991 Jul-Aug;1(4):254-65. doi: 10.2165/00002512-199101040-00002.
本文引用的文献
1
THIAZIDE DIURETICS.噻嗪类利尿剂
Annu Rev Med. 1964;15:149-66. doi: 10.1146/annurev.me.15.020164.001053.
2
Chlorothiazid in diabetes insipidus.氯噻嗪治疗尿崩症。
Nature. 1959 Mar 28;183(4665):891-2. doi: 10.1038/183891a0.
3
Antidiuretic action of chlorpropamide in idiopathic diabetes insipidus.氯磺丙脲在特发性尿崩症中的抗利尿作用。
J Clin Endocrinol Metab. 1966 Dec;26(12):1325-8. doi: 10.1210/jcem-26-12-1325.
4
Relation of extracellular fluid volume to arterial pressure during drug-induced saluresis.药物诱导性利钠期间细胞外液量与动脉压的关系。
Circulation. 1969 Sep;40(3):349-55. doi: 10.1161/01.cir.40.3.349.
5
Oral therapy of diabetes insipidus with chlorpropamide.用氯磺丙脲对尿崩症进行口服治疗。
Calif Med. 1971 Aug;115(2):1-5.
6
Chlorpropamide hyponatremia: drug-induced inappropriate antidiuretic-hormone activity.
N Engl J Med. 1971 Jan 14;284(2):65-71. doi: 10.1056/NEJM197101142840202.
7
Profound hyponatremia resulting from a thiazide-induced decrease in urinary diluting capacity in a patient with primary polydipsia.噻嗪类药物引起的尿稀释能力下降导致原发性烦渴患者出现严重低钠血症。
N Engl J Med. 1970 May 21;282(21):1185-6. doi: 10.1056/NEJM197005212822107.
8
Mechanism of chlorpropamide action in diabetes insipidus.氯磺丙脲治疗尿崩症的作用机制。
J Clin Endocrinol Metab. 1970 Apr;30(4):488-96. doi: 10.1210/jcem-30-4-488.
9
[Preliminary study of antidiuretic effect of clofibrate (or atromid S) in pitressosensitive diabetes insipidus].
Ann Endocrinol (Paris). 1970 Mar-Apr;31(2):300-8.
10
The antidiuretic action of acetaminophen.对乙酰氨基酚的抗利尿作用。
Am J Med Sci. 1966 Oct;252(4):429-35. doi: 10.1097/00000441-196610000-00008.
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