1-乙基-4-（亚异丙基肼基）-1H-吡唑并[3,4-b]吡啶-5-羧酸乙酯盐酸盐（SQ 20009）——一种新型强效环3',5'-核苷酸磷酸二酯酶抑制剂。 - Suppr

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超能文献

1-Ethyl-4-(isopropylidenehydrazino)-1H-pyrazolo-(3,4-b)-pyridine-5-carboxylic acid, ethyl ester, hydrochloride (SQ 20009)--a potent new inhibitor of cyclic 3',5'-nucleotide phosphodiesterases.

作者信息

Chasin M, Harris D N, Phillips M B, Hess S M

出版信息

Biochem Pharmacol. 1972 Sep 15;21(18):2443-50. doi: 10.1016/0006-2952(72)90414-5.

DOI:10.1016/0006-2952(72)90414-5

PMID:4345859

Abstract

摘要

相似文献

1-Ethyl-4-(isopropylidenehydrazino)-1H-pyrazolo-(3,4-b)-pyridine-5-carboxylic acid, ethyl ester, hydrochloride (SQ 20009)--a potent new inhibitor of cyclic 3',5'-nucleotide phosphodiesterases.1-乙基-4-（亚异丙基肼基）-1H-吡唑并[3,4-b]吡啶-5-羧酸乙酯盐酸盐（SQ 20009）——一种新型强效环3',5'-核苷酸磷酸二酯酶抑制剂。

Biochem Pharmacol. 1972 Sep 15;21(18):2443-50. doi: 10.1016/0006-2952(72)90414-5.

Effect of glucagon, dibutyryl adenosine 3',5'-cyclic monophosphate and phosphodiesterase inhibitors on rat liver phosphorylase activity and adenosine 3',5'-cyclic monophosphate levels.胰高血糖素、二丁酰腺苷 3',5'-环磷酸单酯和磷酸二酯酶抑制剂对大鼠肝脏磷酸化酶活性及腺苷 3',5'-环磷酸单酯水平的影响。

Biochem Pharmacol. 1974 Aug;23(15):2139-46. doi: 10.1016/0006-2952(74)90579-6.

Potential antidiabetic agents. Pyrazolo(3,4-b)pyridines.潜在的抗糖尿病药物。吡唑并[3,4 - b]吡啶类

J Med Chem. 1973 Dec;16(12):1340-6. doi: 10.1021/jm00270a006.

Rod outer segment phosphodiesterase: factors affecting the hydrolysis of cyclic-AMP and cyclic-GMP.视杆外段磷酸二酯酶：影响环磷酸腺苷和环磷酸鸟苷水解的因素。

Exp Eye Res. 1974 Jun;18(6):509-15. doi: 10.1016/0014-4835(74)90057-8.

Study of phosphodiesterase inhibitors on lipolysis, phosphodiesterase activity and cyclic 3',5'-adenosine monophosphate levels in isolated fat cells.磷酸二酯酶抑制剂对分离脂肪细胞中脂肪分解、磷酸二酯酶活性及环磷酸腺苷水平的研究。

J Pharmacol Exp Ther. 1973 May;185(2):379-85.

Characteristics of cyclic 3',5'-nucleotide phosphodiesterase from the brain of the Madagascar cockroach (Gromphadorhina portentosa).

Comp Biochem Physiol B. 1974 Jan 15;47(1):189-99. doi: 10.1016/0305-0491(74)90103-5.

Effect of cyclic nucleotides on activity of cyclic 3',5'-adenosine monophosphate phosphodiesterase.环核苷酸对3',5'-环磷酸腺苷磷酸二酯酶活性的影响。

Biochem Pharmacol. 1973 Jan 15;22(2):221-8. doi: 10.1016/0006-2952(73)90275-x.

Characterization of two forms of beef heart cyclic nucleotide phosphodiesterase.两种牛心环核苷酸磷酸二酯酶形式的特性分析。

Biochemistry. 1972 Nov 21;11(24):4458-65. doi: 10.1021/bi00774a006.

Inhibition of 2',3'-cyclic nucleotide 3'-phosphodiesterase activity from bovine, human and guinea pig brain.

Brain Res. 1981 Jun 15;214(2):455-9. doi: 10.1016/0006-8993(81)91212-9.

A comparison of the antilipolytic effects of nicotinic acid, methylisoxazole carboxylic acid, methylpyrazole carboxylic acid and insulin in isolated fat cells.烟酸、甲基异恶唑羧酸、甲基吡唑羧酸及胰岛素对分离脂肪细胞抗脂解作用的比较。

Pharmacology. 1972;8(4):280-90. doi: 10.1159/000136344.

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