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从正常大鼠肝脏和诺维科夫肝癌上清液中分离精氨酸受体蛋白。

Isolation of arginine acceptor-proteins from normal rat liver and Novikoff hepatoma supernatant.

作者信息

Pinard J, de Lamirande G

出版信息

Br J Cancer. 1973 Jan;27(1):18-26. doi: 10.1038/bjc.1973.3.

Abstract

In the present report a procedure for the isolation of more specific arginine receptors from the soluble fraction of rat liver and Novikoff hepatoma is described. In normal rat liver the specific activity of these receptors from the soluble fraction of rat liver and Novikoff hepatoma is described. In normal rat liver the specific activity of these receptors is fifteen times greater than that of the other proteins whereas in the Novikoff it is only three to four times higher. Attempts to sub-fractionate this class of acceptors would seem to indicate a relative homogeneity.

摘要

在本报告中,描述了一种从大鼠肝脏和诺维科夫肝癌的可溶部分中分离出更具特异性的精氨酸受体的方法。在正常大鼠肝脏中,描述了这些受体在大鼠肝脏和诺维科夫肝癌可溶部分中的比活性。在正常大鼠肝脏中,这些受体的比活性比其他蛋白质高15倍,而在诺维科夫肝癌中,仅高3至4倍。对这类受体进行亚分级的尝试似乎表明其相对均一性。

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