Cantwell A R, Kelso D W, Rowe L
Arch Dermatol. 1979 Apr;115(4):449-52.
We described two patients with localized, chronic, painful, scleroderma-like lesions of the lower part of the leg associated with venous stasis. This type of lesion has been termed "hypodermitis sclerodermiformis," and we review the literature pertinent to this entity. In addition, skin biopsy material was studied for the presence of acid-fast microbes. In both cases, Fite-Faraco-stained tissue sections contained many acid-fast coccoid and giant microbial forms suggestive of transitional L forms. Culture of the lesion in both cases was positive for Staphylococcus epidermidis. Until the cause is fully clarified, the search for acid-fast bacteria appears warranted in formed of pseudoscleroderma such as hypodermitis sclerodermiformis.
我们描述了两名患有与静脉淤滞相关的小腿下部局限性、慢性、疼痛性硬皮病样病变的患者。这种病变类型被称为“硬皮病样皮下炎”，我们回顾了与此实体相关的文献。此外，对皮肤活检材料进行了耐酸微生物检测。在这两个病例中，经Fite-Faraco染色的组织切片含有许多耐酸球菌和巨大微生物形态，提示为过渡性L型。两个病例的病变培养均显示表皮葡萄球菌阳性。在硬皮病样病变如硬皮病样皮下炎的情况下，在病因完全明确之前，寻找耐酸细菌似乎是必要的。
