口蹄疫疫苗刺激小鼠产生的抗性，由两种羧酸干扰素诱导剂增强。
Enhancement, by two carboxylic acid interferon inducers of resistance stimulated in mice by foot-and-mouth disease vaccine.
作者信息
Campbell C H, Richmond J Y
出版信息
Infect Immun. 1973 Feb;7(2):199-204. doi: 10.1128/iai.7.2.199-204.1973.
Abstract
Simultaneous injection of divinyl ether-maleic amhydride (DVE/MA) or itaconic-acrylic acid and foot-and-mouth disease virus vaccine enhanced the survival of infant mice to subsequent injections of virus. This enhanced resistance was obtained even with doses of interferon inducers which, when administered alone, failed to protect the mice. There was some increase in serum-neutralizing antibody in mice 7 days after injection of DVE/MA and vaccine, as compared with mice given vaccine alone, but there was no clear connection between antibody level and amount of DVE/MA administered.
摘要
同时注射二乙烯基醚-马来酸酐（DVE/MA）或衣康酸-丙烯酸与口蹄疫病毒疫苗，可提高幼鼠在随后注射病毒时的存活率。即使使用单独给药时无法保护小鼠的干扰素诱导剂剂量，也能获得这种增强的抵抗力。与仅接种疫苗的小鼠相比，注射DVE/MA和疫苗7天后的小鼠血清中和抗体有所增加，但抗体水平与所给予的DVE/MA量之间没有明确的关联。
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引用本文的文献
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Enhancement of primary antigen-specific resistance in infant mice with divinyl ether-maleic anhydride.二乙烯基醚-马来酸酐增强婴儿期小鼠的原发性抗原特异性抗性。
Infect Immun. 1974 Nov;10(5):1029-33. doi: 10.1128/iai.10.5.1029-1033.1974.
2
Foot-and-mouth disease virus: protection induced in infected mice by two orally-administered interferon inducers. Brief report.口蹄疫病毒：两种口服干扰素诱导剂对感染小鼠的保护作用。简报
Arch Gesamte Virusforsch. 1973;42(1):102-5. doi: 10.1007/BF01250512.
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Infect Immun. 1970 Jul;2(1):69-76. doi: 10.1128/iai.2.1.69-76.1970.
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The effect of paraffin oil and mycobacteria on antibody formation and sensitization; a review.石蜡油和分枝杆菌对抗体形成及致敏作用的综述
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