甲氨蝶呤用于赖特综合征。
Methotrexate in Reiter's disease.
作者信息
Owen E T, Cohen M L
出版信息
Ann Rheum Dis. 1979 Feb;38(1):48-50. doi: 10.1136/ard.38.1.48.
Abstract
Three cases of severe Reiter's disease were treated successfully with methotrexate after failure of conservative therapy, including systemic corticosteroids in 2 instances. The usefulness and potential hazards of such therapy are discussed, and some evidence that corticosteroids may aggravate the dermatological manifestations of Reiter's disease is presented.
摘要
3例严重赖特综合征患者在保守治疗（包括2例使用全身性皮质类固醇）失败后，使用甲氨蝶呤成功治愈。本文讨论了该疗法的有效性和潜在风险，并提供了一些证据表明皮质类固醇可能会加重赖特综合征的皮肤表现。
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本文引用的文献
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2
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N Engl J Med. 1974 Mar 7;290(10):554-6. doi: 10.1056/NEJM197403072901008.
3
Reiter's disease: a review with special attention to cardiovascular and neurologic sequellae.赖特综合征：特别关注心血管和神经后遗症的综述
Semin Arthritis Rheum. 1974 Spring;3(3):253-86. doi: 10.1016/0049-0172(74)90021-3.
4
Reiter's disease and HL-A 27.赖特综合征与HL-A 27。
Lancet. 1973 Nov 3;302(7836):996-8. doi: 10.1016/s0140-6736(73)91091-x.
5
The significance of HL-A W27 in ankylosing spondylitis and Reiter's syndrome with three family studies.通过三项家族研究探讨HL-A W27在强直性脊柱炎和赖特综合征中的意义。
Aust N Z J Med. 1975 Apr;5(2):108-11. doi: 10.1111/j.1445-5994.1975.tb03637.x.
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