Sautter R D, Larson D E, Bhattacharyya S K, Chen H M, Treuhaft P S, Milbauer J P, Mazza J J, Emanuel D A, Koch E L, Lolley D M, Myers W O, Ray J F, Plotka E D, Nycz G R, Wenzel F J
Arch Intern Med. 1979 Feb;139(2):148-53.
Using venography as the reference procedure, this study examined the utility of fibrinogen I 125 scanning for the detection or demonstration of deep venous thrombosis. The results demonstrate the inability of leg scanning to detect accurately the presence or absence of thrombi in the deep venous system. Most striking was the lack of sensitivity of this procedure in areas where the propensity for embolization is greatest. Sensitivity is extremely low in the anatomic areas where leg scanning demonstrates reasonable specificity. The results are nearly identical in the extremity not operated upon. The validity of all prior studies relying heavily or exclusively on 125I leg scans to determine the presence or absence of thrombi must be critically reassessed.
以静脉造影作为参照程序，本研究检测了纤维蛋白原I 125扫描在检测或显示深静脉血栓形成方面的效用。结果表明，腿部扫描无法准确检测深静脉系统中血栓的存在与否。最显著的是，该程序在栓塞倾向最大的区域缺乏敏感性。在腿部扫描显示出合理特异性的解剖区域，敏感性极低。在未进行手术的肢体中结果几乎相同。所有严重依赖或仅依靠125I腿部扫描来确定血栓存在与否的先前研究的有效性必须进行严格重新评估。
