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食管闭锁。41年的经验。

Esophageal atresia. A 41-year experience.

作者信息

Strodel W E, Coran A G, Kirsh M M, Weintraub W H, Wesley J R, Sloan H

出版信息

Arch Surg. 1979 Apr;114(4):523-7. doi: 10.1001/archsurg.1979.01370280177030.

Abstract

Since the first attempted repair in 1935, a total of 365 infants have undergone treatment for esophageal atresia with or without tracheoesophageal fistula. To evaluate the improvement in our results, we have divided our patients into four, approximately equal, time periods. The overall late survival has indeed improved during each of the four decades from between 36% and 53% to 68% in the last ten years. During this past decade, the group A risk infants (35 patients) had a 3% mortality, the group B (20 patients) had a 5% mortality, but the group C babies (22 patients) had a 41% mortality due to associated anomalies or severe prematurity. Anastomotic leaks and recurrent fistulas were each encountered in approximately 5% of the cases in all decades. Postoperative stricture has been encountered in 20% of the entire series and no esophageal replacements have been required.

摘要

自1935年首次尝试修复以来,共有365例患有或不患有气管食管瘘的食管闭锁婴儿接受了治疗。为了评估我们治疗结果的改善情况,我们将患者分为四个大致相等的时间段。在过去的四十年里,总体晚期生存率确实有所提高,从36%至53%提高到了过去十年的68%。在过去十年中,A组风险婴儿(35例)死亡率为3%,B组(20例)死亡率为5%,但C组婴儿(22例)由于合并畸形或严重早产,死亡率为41%。在所有十年中,吻合口漏和复发性瘘在大约5%的病例中均有出现。术后狭窄在整个系列病例中占20%,且无需进行食管替代。

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