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Synthesis of 6'-cyano-6'-deoxyhomoadenosine-6'-phosphonic acid and its phosphoryl and pyrophosphoryl anhydrides and studies of their interactions with adenine nucleotide utilizing enzymes.

作者信息

Hampton A, Sasaki T, Paul B

出版信息

J Am Chem Soc. 1973 Jun 27;95(13):4404-14. doi: 10.1021/ja00794a043.

DOI:10.1021/ja00794a043
PMID:4350696
Abstract
摘要

相似文献

1
Synthesis of 6'-cyano-6'-deoxyhomoadenosine-6'-phosphonic acid and its phosphoryl and pyrophosphoryl anhydrides and studies of their interactions with adenine nucleotide utilizing enzymes.6'-氰基-6'-脱氧高腺苷-6'-膦酸及其磷酰和焦磷酰酐的合成以及利用酶对它们与腺嘌呤核苷酸相互作用的研究。
J Am Chem Soc. 1973 Jun 27;95(13):4404-14. doi: 10.1021/ja00794a043.
2
Synthesis of homoadenosine-6'-phosphonic acid and studies of its substrate and inhibitor properties with adenosine monophosphate utilizing enzymes.
Biochemistry. 1973 Apr 24;12(9):1730-6. doi: 10.1021/bi00733a011.
3
The potential of carboxylic-phosphoric mixed anhydrides as specific reagents for enzymic binding sites for alkyl phosphates. Inactivation of an enzyme by an anhydride isosteric with adenosine 5'-phosphate.羧酸 - 磷酸混合酸酐作为烷基磷酸酯酶结合位点特异性试剂的潜力。一种与5'-磷酸腺苷等排的酸酐使酶失活。
Arch Biochem Biophys. 1971 Mar;143(1):340-1. doi: 10.1016/0003-9861(71)90217-7.
4
Evidence for the conformation of enzyme-bound adenosine 5'-phosphate. Substrate and inhibitor properties of 8,5' -cycloadenosine 5'-phosphate with adenylate kinase, adenylate aminohydrolase, adenylosuccinate lyase, and 5'-nucleotidase.
Biochemistry. 1972 Dec 19;11(26):4965-9. doi: 10.1021/bi00776a014.
5
Interactions of the epimeric 5'-C-methyl and 5'-C-carbamyl derivatives of adenosine monophosphate with adenosine monophosphate utilizing enzymes.腺苷一磷酸的差向异构5'-C-甲基和5'-C-氨甲酰基衍生物与利用腺苷一磷酸的酶的相互作用。
Biochemistry. 1973 Aug 14;12(17):3328-32. doi: 10.1021/bi00741a027.
6
[Chemical synthesis of nucleotides. Synthesis of mononucleotides and nucleotide anhydrides].[核苷酸的化学合成。单核苷酸和核苷酸酐的合成]
Tanpakushitsu Kakusan Koso. 1968:Suppl:80-112.
7
[Methods of preparation of P-32-labeled nucleosidetriphosphates in alpha and gamma position].[α和γ位P-32标记的核苷三磷酸的制备方法]
Postepy Biochem. 1983;29(3-4):377-92.
8
Interaction between adenine nucleotides and 3-phosphoglyceraldehyde dehydrogenase. II. A study of the mechanism of catalysis and metabolic control of the multi-functional enzyme.
J Biol Chem. 1971 Sep 10;246(17):5433-41.
9
Inhibition of rabbit skeletal muscle adenylate kinase by the transition state analogue, P 1 ,P 4 -di(adenosine-5')tetraphosphate.过渡态类似物P1，P4 - 二（腺苷 - 5'）四磷酸对兔骨骼肌腺苷酸激酶的抑制作用
Biochim Biophys Acta. 1972 Aug 28;276(2):563-7. doi: 10.1016/0005-2744(72)91021-2.
10
Design of substrate-site-directed inhibitors of adenylate kinase and hexokinase. Effect of substrate substituents on affinity on affinity for the adenine nucleotide sites.
J Med Chem. 1976 Dec;19(12):1371-7. doi: 10.1021/jm00234a004.

引用本文的文献

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Analogues of the Natural Product Sinefungin as Inhibitors of EHMT1 and EHMT2.作为EHMT1和EHMT2抑制剂的天然产物西尼芬净类似物
ACS Med Chem Lett. 2014 Jan 31;5(4):293-7. doi: 10.1021/ml4002503. eCollection 2014 Apr 10.
2
The potential of nucleotide analogs as inhibitors of retroviruses and tumors.核苷酸类似物作为逆转录病毒和肿瘤抑制剂的潜力。
Pharm Res. 1984 Jan;1(1):11-8. doi: 10.1023/A:1016370407633.
3
Identification by photo-affinity labeling of the proteins in Escherichia coli ribosomes involved in elongation factor G-dependent GDP binding.
通过光亲和标记鉴定大肠杆菌核糖体中参与延伸因子G依赖性GDP结合的蛋白质。
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1277-80. doi: 10.1073/pnas.71.4.1277.
4
Dehydration of a phosphonate substrate analogue by glycerol 3-phosphate dehydrogenase.甘油3-磷酸脱氢酶催化膦酸酯底物类似物的脱水反应。
Biochem J. 1974 Sep;141(3):729-32. doi: 10.1042/bj1410729.