Okon E, Rosenmann E, Dishon T, Boss J H
Br J Cancer. 1973 May;27(5):362-9. doi: 10.1038/bjc.1973.44.
Urine of normal rats, pregnant animals and animals bearing chemically induced hepatoma was tested with antisera to foetoproteins by the double immunodiffusion technique. Antigens were not detected in the urine of normal rats. Alpha-foetoprotein was demonstrated in the urine of pregnant rats and hepatomabearing animals.
采用双向免疫扩散技术,用抗胎儿蛋白抗血清检测正常大鼠、妊娠动物和化学诱导肝癌动物的尿液。在正常大鼠尿液中未检测到抗原。在妊娠大鼠和患肝癌动物的尿液中证实有甲胎蛋白。