通过免疫电子显微镜对与鼠肉瘤病毒相关的细胞表面抗原的展示。
Demonstration of a cell-surface antigen associated with murine sarcoma virus by immunoelectron microscopy.
作者信息
Aoki T, Stephenson J R, Aaronson S A
出版信息
Proc Natl Acad Sci U S A. 1973 Mar;70(3):742-6. doi: 10.1073/pnas.70.3.742.
Cells transformed by murine sarcoma virus have been examined for the presence of a new virus-associated cell-surface antigen by immunoelectron microscopy. A common antigen has been detected on the surface of nonproductively transformed cells that were induced by two different strains of murine sarcoma virus, Kirsten and Moloney. This antigen shows crossreaction with cell lines transformed by murine sarcoma virus that were produced in two different mammalian species, rats and mice. Further, this antigen is distinct from previously described antigens on the surfaces of cells infected by murine leukemia virus, on the viral envelope, and on the surfaces of spontaneously transformed cell lines or cell lines transformed by x-irradiation.
通过免疫电子显微镜检查了由鼠肉瘤病毒转化的细胞，以确定是否存在一种新的病毒相关细胞表面抗原。在由两种不同株的鼠肉瘤病毒（Kirsten株和Moloney株）诱导的非生产性转化细胞表面检测到了一种共同抗原。这种抗原与在两种不同哺乳动物物种（大鼠和小鼠）中产生的由鼠肉瘤病毒转化的细胞系发生交叉反应。此外，这种抗原与先前描述的感染鼠白血病病毒的细胞表面、病毒包膜以及自发转化细胞系或经x射线照射转化的细胞系表面的抗原不同。
Zotero 插件