聚尿苷酸与兔珠蛋白信使核糖核酸之间的相互作用。
Interaction between polyuridylic acid and rabbit globin messenger ribonucleic acid.
作者信息
Hunt J A
出版信息
Biochem J. 1973 Feb;131(2):327-33. doi: 10.1042/bj1310327.
Abstract
Poly(U) binds to globin mRNA in 0.1m-NaCl. Studies with ribonuclease digestion of this complex suggest that there are polyadenylate-rich sequences in the mRNA containing about 30-40 adenylate residues. The sequences appear to be homogenous and of approximately the same length for both alpha- and beta-globin mRNA. They are most likely located at the 3' terminus of the molecule.
摘要
在0.1m氯化钠溶液中，聚尿苷酸（Poly(U)）与珠蛋白信使核糖核酸（globin mRNA）结合。对该复合物进行核糖核酸酶消化的研究表明，信使核糖核酸中存在富含聚腺苷酸的序列，其中约含有30 - 40个腺苷酸残基。对于α-珠蛋白信使核糖核酸和β-珠蛋白信使核糖核酸而言，这些序列似乎是同源的，且长度大致相同。它们很可能位于分子的3'末端。
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