Mufson M A, Levine H D, Wasil R E, Mocega-Gonzalez H E, Krause H E
Am J Epidemiol. 1973 Aug;98(2):88-95. doi: 10.1093/oxfordjournals.aje.a121542.
From January 1, 1967 to December 1971, the temporal pattern of respiratory syncytial virus infection was investigated in infants and children younger than 18 months hospitalized for acute lower respiratory tract disease. Of 4696 infants and children with acute lower respiratory tract disease admitted to the Cook County Hospital, 2530 were tested for virus infection by virus isolation or serologic procedures or both. Overall, respiratory syncytial virus infections were detected in 12% and parainfluenza 3 virus in 10.8% of individuals tested. Other respiratory viruses were less commonly identified. Respiratory syncytial virus epidemics occurred annually and were temporally synchronous with the peak periods of respiratory disease admissions. Only during epidemics of respiratory syncytial virus did admission for respiratory tract disease usually reach 40 patients or more weekly. The peak months of respiratory syncytial virus epidemics were December 1966, January 1968, February-March 1969, April 1970 and January 1971. Epidemics lasted about 17 weeks. No similar annual epidemic pattern was seen with the other myxoviruses.
1967年1月1日至1971年12月，对因急性下呼吸道疾病住院的18个月以下婴幼儿的呼吸道合胞病毒感染的时间模式进行了调查。在库克县医院收治的4696例患有急性下呼吸道疾病的婴幼儿中，2530例通过病毒分离或血清学方法或两者兼用进行了病毒感染检测。总体而言，在接受检测的个体中，12%检测出呼吸道合胞病毒感染，10.8%检测出副流感3型病毒感染。其他呼吸道病毒的检出率较低。呼吸道合胞病毒每年都会流行，且在时间上与呼吸道疾病住院高峰期同步。仅在呼吸道合胞病毒流行期间，呼吸道疾病的每周住院人数通常达到40人或更多。呼吸道合胞病毒流行的高峰月份为1966年12月、1968年1月、1969年2月至3月、1970年4月和1971年1月。疫情持续约17周。其他黏液病毒未出现类似的年度流行模式。
