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[暴露于紫外线下的线粒体中荧光产物的形成]

[Formation of fluorescent products in mitochondria exposed to UV-light].

作者信息

Popov G A, Konev V V

出版信息

Biofizika. 1979 Jan-Feb;24(1):168-70.

PMID:435531
Abstract

UV-irradiation of mitochondrial membranes causes formation and accumulation of fluorescing products in the course of incubation, like it takes place during the initiation of peroxide oxidation by the iron--ascorbate system. The rate of the change of mitochondria fluorescence and the level of TBA-products in them do not correlate, which points to the difference in the formation mechanisms of these products in the course of incubation. However, a correlation is observed between the initial fluorescence intensity and the number of TBA-active products in mitochondria, which increases with the increase of the time of UV-irradiation.

摘要

线粒体膜的紫外线照射会在孵育过程中导致荧光产物的形成和积累,就如同铁 - 抗坏血酸系统引发过氧化物氧化时所发生的那样。线粒体荧光变化的速率与其内硫代巴比妥酸(TBA)产物的水平并无关联,这表明在孵育过程中这些产物的形成机制存在差异。然而,在线粒体的初始荧光强度与TBA活性产物数量之间观察到了一种相关性,且随着紫外线照射时间的增加而增强。

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