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培养的小鼠卵裂期胚胎和原始性畸胎瘤细胞共有的表面抗原。

Surface antigens common to mouse cleavage embryos and primitive teratocarcinoma cells in culture.

作者信息

Artzt K, Dubois P, Bennett D, Condamine H, Babinet C, Jacob F

出版信息

Proc Natl Acad Sci U S A. 1973 Oct;70(10):2988-92. doi: 10.1073/pnas.70.10.2988.

DOI:10.1073/pnas.70.10.2988
PMID:4355379
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC427153/
Abstract

Syngeneic antisera have been produced in mouse strain 129/Sv-CP males against the primitive cells of teratocarcinoma. These sera react specifically with the primitive cells and are negative on various types of differentiated teratoma cells derived from the same original tumor. They are negative on all other mouse cells tested, with the exception of male germ cells and cleavage-stage embryos. Thus, teratoma cells possess cell-surface antigens in common with normal cleavage-stage embryos.

摘要

在129/Sv-CP雄性小鼠品系中制备了同基因抗血清,用于对抗畸胎癌的原始细胞。这些血清与原始细胞发生特异性反应,而对源自同一原始肿瘤的各种分化型畸胎瘤细胞呈阴性反应。除雄性生殖细胞和卵裂期胚胎外,它们对所有其他测试的小鼠细胞均呈阴性。因此,畸胎瘤细胞与正常卵裂期胚胎具有共同的细胞表面抗原。

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Surface antigens common to mouse cleavage embryos and primitive teratocarcinoma cells in culture.培养的小鼠卵裂期胚胎和原始性畸胎瘤细胞共有的表面抗原。
Proc Natl Acad Sci U S A. 1973 Oct;70(10):2988-92. doi: 10.1073/pnas.70.10.2988.
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Presence of a mouse embryonic antigen on human spermatozoa.人类精子上存在小鼠胚胎抗原。
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本文引用的文献

1
CYTOCHEMICAL DEMONSTRATION OF PEROXIDASE ACTIVITY WITH 3-AMINO-9-ETHYLCARBAZOLE.用3-氨基-9-乙基咔唑进行过氧化物酶活性的细胞化学显示
J Histochem Cytochem. 1965 Feb;13:150-2. doi: 10.1177/13.2.150.
2
SUCCESSIVE TRANSFORMATIONS OF AN ESTABLISHED CELL LINE BY POLYOMA VIRUS AND SV40.多瘤病毒和猿猴空泡病毒40对一个既定细胞系的连续转化
Science. 1965 Jan 29;147(3657):513-4. doi: 10.1126/science.147.3657.513.
3
FORMATION OF GENETICALLY MOSAIC MOUSE EMBRYOS, AND EARLY DEVELOPMENT OF "LETHAL (T12/T12)-NORMAL" MOSAICS.基因嵌合小鼠胚胎的形成以及“致死型(T12/T12)-正常型”嵌合体的早期发育
人类多能干细胞的起源:从癌症到再生医学的道路。
In Vitro Cell Dev Biol Anim. 2024 May;60(5):514-520. doi: 10.1007/s11626-024-00865-8. Epub 2024 Feb 23.
4
A short history of pluripotent stem cells markers.多能干细胞标志物的简史。
Stem Cell Reports. 2024 Jan 9;19(1):1-10. doi: 10.1016/j.stemcr.2023.11.012. Epub 2023 Dec 28.
5
The application of cell surface markers to demarcate distinct human pluripotent states.细胞表面标志物在区分人类多能状态中的应用。
Exp Cell Res. 2020 Feb 1;387(1):111749. doi: 10.1016/j.yexcr.2019.111749. Epub 2019 Nov 30.
6
Nucleic acid synthesis in preimplantation mouse embryos : Autoradiographic evidence of uridine and deoxyuridine utilization in DNA synthesis.植入前小鼠胚胎中的核酸合成:DNA合成中尿苷和脱氧尿苷利用的放射自显影证据。
Wilehm Roux Arch Dev Biol. 1977 Sep;181(3):193-202. doi: 10.1007/BF00848420.
7
Embryoglycan: a highly branched poly-N-acetyllactosamine in pluripotent stem cells and early embryonic cells.胚胎糖蛋白:多能干细胞和早期胚胎细胞中的高度分支多 N-乙酰乳糖胺。
Glycoconj J. 2017 Dec;34(6):701-712. doi: 10.1007/s10719-016-9673-3. Epub 2016 May 17.
8
The Wistar legacy to embryonic stem cell research.威斯塔对胚胎干细胞研究的贡献。
Monoclon Antib Immunodiagn Immunother. 2014 Jun;33(3):154-7. doi: 10.1089/mab.2014.0003. Epub 2014 Jun 3.
9
Asynchronous transcriptional silencing of individual retroviral genomes in embryonic cells.胚胎细胞中单个逆转录病毒基因组的异步转录沉默
Retrovirology. 2014 Apr 17;11:31. doi: 10.1186/1742-4690-11-31.
10
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Immunogenetics. 1980;10(6):607-12. doi: 10.1007/BF01572595.
J Exp Zool. 1964 Nov;157:273-92. doi: 10.1002/jez.1401570210.
4
Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines.对培养的小鼠胚胎细胞生长及其发育成既定细胞系的定量研究。
J Cell Biol. 1963 May;17(2):299-313. doi: 10.1083/jcb.17.2.299.
5
Studies on transplantable testicular teratomas of strain 129 mice.129品系小鼠可移植性睾丸畸胎瘤的研究。
J Natl Cancer Inst. 1958 Jun;20(6):1257-75. doi: 10.1093/jnci/20.6.1257.
6
The nature of gliomas as revealed by animal experimentation.动物实验所揭示的胶质瘤的本质。
Am J Pathol. 1955 Jan-Feb;31(1):1-29.
7
[Induction of isogenic Gross virus leukaemia in adult C57Bl-6 mice by repeated injections of AkR leukemic cells].
Rev Fr Etud Clin Biol. 1969 Jun-Jul;14(6):587-9.
8
Detection of H-2 antigens on mouse spermatozoa by the cytotoxicity test.通过细胞毒性试验检测小鼠精子上的H-2抗原。
Nature. 1970 Nov 7;228(5271):570-2. doi: 10.1038/228570a0.
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10
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Cancer. 1970 Mar;25(3):644-58. doi: 10.1002/1097-0142(197003)25:3<644::aid-cncr2820250321>3.0.co;2-g.