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[工作性充血条件下骨骼肌微循环床血管通透性的变化]

[Change in the permeability of vessels in the microcirculatory bed of skeletal muscles in conditions of working hyperemia].

作者信息

Vasil'ev N D, Kozlov V I

出版信息

Biull Eksp Biol Med. 1979 Apr;87(4):369-71.

PMID:435633
Abstract

Permeability of m. quadriceps femoris and m. gastrocnemius mimicrocirculatory bed of albino rats was studied by fluorescent biomicroscopy at rest and under work hyperemia. Fluorescein-labeled bovine globulin (FBG) was used as an indicator of permeability alteration. Quantitative fluorescent analysis was carried out on a microspectrofluorimeter. In work hypermia the FBG concentration in the muscle exceeded such at rest by 40--45%; this evidenced an increased transendothelial transport. The results of the experiments on the measurement of FBG concentration about a single capillary suggested that the microcirculatory bed permeability increased under work hyperemia.

摘要

采用荧光显微镜技术,对白化大鼠股四头肌和腓肠肌微循环床在静息状态及运动性充血状态下的通透性进行了研究。用荧光素标记的牛血清球蛋白(FBG)作为通透性改变的指示剂。在显微分光荧光计上进行定量荧光分析。在运动性充血状态下,肌肉中FBG的浓度比静息状态时高出40% - 45%;这证明经内皮转运增加。关于单个毛细血管周围FBG浓度测量的实验结果表明,在运动性充血状态下微循环床的通透性增加。

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1
[Change in the permeability of vessels in the microcirculatory bed of skeletal muscles in conditions of working hyperemia].[工作性充血条件下骨骼肌微循环床血管通透性的变化]
Biull Eksp Biol Med. 1979 Apr;87(4):369-71.
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[Morphometric characteristics of the microcirculatory bed of a skeletal muscle during work hyperemia].[工作性充血期间骨骼肌微循环床的形态计量学特征]
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