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暴露于低氧环境下的大鼠组织中酶活性的变化。

Changes in enzyme activities in tissues of rats exposed to hypoxia.

作者信息

Cryer A, Bartley W

出版信息

Biochem J. 1973 Aug;134(4):1119-22. doi: 10.1042/bj1341119.

DOI:10.1042/bj1341119
PMID:4357712
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1177921/
Abstract

Rats were exposed to various degrees of hypoxia and enzyme activities in their tissues were determined. In general, oxidative metabolism was not increased in response to hypoxia, nor was anaerobic metabolism. Physiological and anatomical changes were concluded to be more important than changes in cellular enzyme activities in the overall adaptation to acute hypoxia.

摘要

将大鼠暴露于不同程度的低氧环境中,并测定其组织中的酶活性。一般来说,低氧状态下氧化代谢并未增加,无氧代谢也未增加。在对急性低氧的整体适应过程中,生理和解剖学变化被认为比细胞酶活性的变化更为重要。

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本文引用的文献

1
Myoglobin content and enzymatic activity of muscle and altitude adaptation.肌肉的肌红蛋白含量、酶活性与海拔适应
J Appl Physiol. 1962 Mar;17:301-5. doi: 10.1152/jappl.1962.17.2.301.
2
CELLULAR TRANSPORT OF LONG CHAIN FATTY ACIDS.长链脂肪酸的细胞转运
Can J Biochem. 1964 Jun;42:955-69. doi: 10.1139/o64-107.
3
Evolution and differentiation of dehvdrogenases.脱氢酶的进化与分化。 (注:原文中“dehvdrogenases”拼写错误,正确应为“dehydrogenases”)
Ann N Y Acad Sci. 1961 Nov 2;94:701-22. doi: 10.1111/j.1749-6632.1961.tb35567.x.
4
Alterations in enzymes and metabolites resulting from adaptation to low oxygen tensions.因适应低氧张力而导致的酶和代谢物的变化。
Am J Physiol. 1957 Jul;190(1):93-8. doi: 10.1152/ajplegacy.1957.190.1.93.
5
Age differences in response to chronic hypoxia on the fine structure of cardiac muscle and autonomic ganglion cells.慢性低氧对心肌和自主神经节细胞超微结构影响的年龄差异
J Gerontol. 1967 Oct;22(4):485-501.
6
Myocardial uptake and fractional distribution of palmitate-1 C14 by the ischemic dog heart.缺血犬心脏对棕榈酸 -1 C14的心肌摄取及分数分布
Metabolism. 1966 Oct;15(10):945-54. doi: 10.1016/0026-0495(66)90165-x.
7
An electron microscopic study of the effects of chronic hypoxia on cardiac muscle, hepatic, and autonomic ganglion cells.慢性缺氧对心肌、肝脏和自主神经节细胞影响的电子显微镜研究。
Lab Invest. 1965 Aug;14(8):1523-46.
8
The kinetics of enzyme changes in yeast under conditions that cause the loss of mitochondria.在导致线粒体丢失的条件下酵母中酶变化的动力学
Biochem J. 1968 Apr;107(4):455-65. doi: 10.1042/bj1070455.
9
Long chain fatty acid activation in subcellular preparations from rat liver.大鼠肝脏亚细胞制剂中的长链脂肪酸活化
J Biol Chem. 1968 Jan 25;243(2):352-61.
10
Activation of liver succinate dehydrogenase in rats exposed to hypobaric conditions.低压环境下大鼠肝脏琥珀酸脱氢酶的激活
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