哺乳动物肝细胞培养中芳烃羟化酶的诱导作用。IV. 对源自大鼠或小鼠肝癌及正常大鼠肝脏的已建细胞系中该酶活性的刺激作用。 - Suppr

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Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. IV. Stimulation of the enzyme activity in established cell lines derived from rat or mouse hepatoma and from normal rat liver.

作者信息

Benedict W F, Gielen J E, Owens I S, Niwa A, Bebert D W

出版信息

Biochem Pharmacol. 1973 Nov 1;22(21):2766-9. doi: 10.1016/0006-2952(73)90138-x.

DOI:10.1016/0006-2952(73)90138-x

PMID:4357894

Abstract

摘要

相似文献

Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. IV. Stimulation of the enzyme activity in established cell lines derived from rat or mouse hepatoma and from normal rat liver.哺乳动物肝细胞培养中芳烃羟化酶的诱导作用。IV. 对源自大鼠或小鼠肝癌及正常大鼠肝脏的已建细胞系中该酶活性的刺激作用。

Biochem Pharmacol. 1973 Nov 1;22(21):2766-9. doi: 10.1016/0006-2952(73)90138-x.

Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. I. Stimulation of enzyme activity in nonhepatic cells and in hepatic cells by phenobarbital, polycyclic hydrocarbons, and 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane.哺乳动物肝细胞培养中芳烃羟化酶的诱导。I. 苯巴比妥、多环烃和2,2-双（对氯苯基）-1,1,1-三氯乙烷对非肝细胞和肝细胞中酶活性的刺激作用

J Biol Chem. 1971 Sep 10;246(17):5189-98.

Polycyclic hydrocarbon-produced toxicity, transformation, and chromosomal aberrations as a function of aryl hydrocarbon hydroxylase activity in cell cultures.多环烃在细胞培养物中产生的毒性、转化及染色体畸变与芳烃羟化酶活性的关系。

Int J Cancer. 1972 Mar 15;9(2):435-51. doi: 10.1002/ijc.2910090223.

Benzpyrene hydroxylase activity and its induction by methylcholanthrene in Morris hepatomas, in host livers, in adult livers, and in rat liver during development.苯并芘羟化酶活性及其在莫里斯肝癌、宿主肝脏、成年肝脏以及发育过程中大鼠肝脏中被甲基胆蒽诱导的情况。

Cancer Res. 1970 Feb;30(2):263-73.

Aryl hydrocarbon hydroxylase induction in mammalian liver-derived cell cultures. Stimulation of "cytochrome P1-450-associated" enzyme activity by many inducing compounds.哺乳动物肝脏来源细胞培养物中芳烃羟化酶的诱导。许多诱导化合物对“细胞色素P1-450相关”酶活性的刺激。

Mol Pharmacol. 1975 Jan;11(1):94-104.

The in vivo and in vitro induction of aryl hydrocarbon hydroxylase in mammalian cells of different species, tissues, strains, and developmental and hormonal states.不同物种、组织、品系以及处于不同发育阶段和激素状态的哺乳动物细胞中芳烃羟化酶的体内和体外诱导。

Arch Biochem Biophys. 1969 Oct;134(1):76-89. doi: 10.1016/0003-9861(69)90253-7.

Expression of cytochromes P-450 in rat hepatoma cells. Analysis by monoclonal antibodies specific for cytochromes P-450 from rat liver induced by 3-methylcholanthrene or phenobarbital.大鼠肝癌细胞中细胞色素P-450的表达。用针对由3-甲基胆蒽或苯巴比妥诱导的大鼠肝脏细胞色素P-450的单克隆抗体进行分析。

Eur J Biochem. 1984 Dec 17;145(3):455-62. doi: 10.1111/j.1432-1033.1984.tb08577.x.

Aryl hydrocarbon (benzo ( ) pyrene) hydroxylase: inducible in extrahepatic tissues of mouse strains not inducible in liver.芳基烃（苯并（α）芘）羟化酶：在小鼠品系的肝外组织中可诱导，而在肝脏中不可诱导。

Arch Biochem Biophys. 1973 Jan;154(1):292-4. doi: 10.1016/0003-9861(73)90060-x.

Genetic differences in aryl hydrocarbon hydroxylase induction and benzo(a)pyrene-produced tumorigenesis in the mouse.小鼠中芳烃羟化酶诱导及苯并(a)芘所致肿瘤发生的遗传差异。

Mol Pharmacol. 1973 Mar;9(2):266-77.

Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. II. Effects of actinomycin D and cycloheximide on induction processes by phenobarbital or polycyclic hydrocarbons.哺乳动物肝细胞培养中芳烃羟化酶的诱导作用。II. 放线菌素D和环己酰亚胺对苯巴比妥或多环烃诱导过程的影响。

J Biol Chem. 1971 Sep 10;246(17):5199-206.

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Induction of aryl hydrocarbon (benzo(a)pyrene) hydroxylase and tyrosine aminotransferase in hepatoma cells in culture.培养的肝癌细胞中芳烃（苯并(a)芘）羟化酶和酪氨酸转氨酶的诱导作用。

J Cell Biol. 1974 Oct;63(1):136-45. doi: 10.1083/jcb.63.1.136.

Analysis of two benzo[a]pyrene-resistant mutants of the mouse hepatoma Hepa-1 P(1)450 gene via cDNA expression in yeast.通过在酵母中进行cDNA表达对小鼠肝癌Hepa-1 P(1)450基因的两个苯并[a]芘抗性突变体进行分析。

EMBO J. 1987 Jul;6(7):1929-33. doi: 10.1002/j.1460-2075.1987.tb02453.x.

Induction of NAD(P)H:quinone reductase in murine hepatoma cells by phenolic antioxidants, azo dyes, and other chemoprotectors: a model system for the study of anticarcinogens.酚类抗氧化剂、偶氮染料及其他化学保护剂对小鼠肝癌细胞中NAD(P)H:醌还原酶的诱导作用：一种用于研究抗癌剂的模型系统

Proc Natl Acad Sci U S A. 1986 Feb;83(3):787-91. doi: 10.1073/pnas.83.3.787.

Monoclonal antibodies to the pituitary growth-hormone receptor by the anti-idiotypic approach. Production and initial characterization.通过抗独特型方法制备垂体生长激素受体单克隆抗体。制备及初步特性鉴定。

Biochem J. 1990 Mar 1;266(2):467-74. doi: 10.1042/bj2660467.

Dioxin-dependent activation of murine Cyp1a-1 gene transcription requires protein kinase C-dependent phosphorylation.二噁英依赖的小鼠Cyp1a-1基因转录激活需要蛋白激酶C依赖的磷酸化作用。

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Proc Natl Acad Sci U S A. 1979 Jan;76(1):373-6. doi: 10.1073/pnas.76.1.373.

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