Sundaram T K
J Bacteriol. 1972 Jul;111(1):284-6. doi: 10.1128/jb.111.1.284-286.1972.
A mutant of Aerobacter aerogenes produces constitutively the series of enzymes that mediates the degradation of myo-inositol and which in the wildtype strain is inducible. When grown on l-histidine, the mutant forms the enzymes at a level approximately three times as high as that seen in the induced wild type. The enzymes appear to be coordinately regulated and are sensitive to catabolite repression. Unless repressed, the synthesis of these enzymes markedly retards the growth of the mutant.
产气气杆菌的一个突变体组成型地产生一系列介导肌醇降解的酶，而在野生型菌株中这些酶是可诱导的。当在L-组氨酸上生长时，该突变体形成这些酶的水平约为诱导型野生型的三倍。这些酶似乎是协同调节的，并且对分解代谢物阻遏敏感。除非受到抑制，这些酶的合成会显著延缓突变体的生长。
