Holmberg D L, Presnell K R
Can Vet J. 1979 Mar;20(3):78-81.
During early fetal life six pair of aortic arches surround the esophagus and trachea. Normal maturation and selective regression of these structures form the adult vasculature. Abnormal location or development of the aortic arches may result in pressure on adjacent organs. Vascular ring anomalies must be considered with any patient with a history of regurgitating food shortly after eating. Physical examination, test feedings, survey and contrast radiographs may give an accurate impression of the problem but a final diagnosis can only be made following surgical exploration. In the case presented, the dog had all the clinical and diagnostic signs suggestive of a vascular ring anomaly. Thoracotomy and elimination of the vascular constriction around the esophagus was both diagnostic and therapeutic for the condition. It is important that owners be made aware that surgical correction of the stenosis does not guarantee a successful conclusion to the case. If the dilation of the esophagus cranial to the stenosis is severe, accumulation of food with subsequent regurgitation may persist. A dilation of the esophagus caudal to the stenosis is present in a large percentage of cases and this also may result in an unrelenting problem. Unfortunately, the probability of these complications cannot be accurately evaluated prior to treatment.The hereditary potential for this defect must also be considered. Congenital vascular anomalies such as patent ductus arteriosus would seem to have a hereditary basis. Therefore, it is probably correct to advise against breeding affected animals. Further, the inbreeding of nonaffected animals which come from litters containing affected animals should be avoided.
在胎儿早期，六对主动脉弓环绕着食管和气管。这些结构的正常成熟和选择性退化形成了成人的脉管系统。主动脉弓的位置异常或发育异常可能会对相邻器官造成压迫。对于任何有进食后不久反流食物病史的患者，都必须考虑血管环异常。体格检查、试喂、X线平片和造影X线片可能会对问题给出准确的印象，但只有在手术探查后才能做出最终诊断。在本文所述的病例中，这只狗具有所有提示血管环异常的临床和诊断体征。开胸手术并消除食管周围的血管狭窄对该病具有诊断和治疗作用。重要的是要让主人意识到，对狭窄进行手术矫正并不能保证病例有成功的结果。如果狭窄上方的食管扩张严重，食物积聚及随后的反流可能会持续存在。在很大比例的病例中，狭窄下方的食管会出现扩张，这也可能导致一个持续存在的问题。不幸的是，在治疗前无法准确评估这些并发症的可能性。还必须考虑这种缺陷的遗传可能性。诸如动脉导管未闭等先天性血管异常似乎有遗传基础。因此，建议不要繁殖受影响的动物可能是正确的。此外，应避免对来自含有受影响动物的一窝动物中的未受影响动物进行近亲繁殖。
