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Insulin interactions with its receptors: experimental evidence for negative cooperativity.

作者信息

de Meyts P, Roth J, Neville D M, Gavin J R, Lesniak M A

出版信息

Biochem Biophys Res Commun. 1973 Nov 1;55(1):154-61. doi: 10.1016/s0006-291x(73)80072-5.

DOI:10.1016/s0006-291x(73)80072-5
PMID:4361269
Abstract
摘要

相似文献

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Insulin interactions with its receptors: experimental evidence for negative cooperativity.胰岛素与其受体的相互作用:负协同性的实验证据。
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Glycosylation of cell surface receptors: tunicamycin treatment decreases insulin and growth hormone binding to different levels in cultured lymphocytes.
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Receptor-mediated degradation of human growth hormone in rat adipocytes and cultured human lymphocytes (IM-9).大鼠脂肪细胞和培养的人淋巴细胞(IM-9)中受体介导的人生长激素降解
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The human lymphocyte: a model for the study of insulin-receptor interaction.人类淋巴细胞:胰岛素受体相互作用研究的模型。
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Intracellular potassium depletion in IM-9 lymphocytes suppresses the slowly dissociating component of human growth hormone binding and the down-regulation of its receptors but does not affect insulin receptors.IM-9淋巴细胞内的钾离子耗竭会抑制人生长激素结合的缓慢解离成分及其受体的下调,但不影响胰岛素受体。
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