传染性肝炎患者澳大利亚抗原阴性血清中抗腺病毒、巨细胞病毒和风疹病毒的抗体
Antibodies against adeno-, cytomegalo and rubella viruses in Australia-antigen-negative sera from patients with infectious hepatitis.
作者信息
Alwen J, Emmerson A M
出版信息
J Hyg (Lond). 1974 Jun;72(3):433-9. doi: 10.1017/s0022172400023676.
Antibodies neutralizing adenovirus type 5 were found in all of 50 pairs (100%) of sera from patients with acute icteric infectious hepatitis. The incidence in sera from the general population was 57%. No differences in mean titre or in proportion of positive sera were found in the same sera tested for complement-fixing antibodies to cytomegalovirus and for antibodies to rubella virus haemagglutinin. The results can be interpreted as supporting the involvement, either direct or indirect, of adenovirus in the aetiology of infectious hepatitis; but could also be due to a non-specific anamnestic enhancement of the production of antibody to adenovirus, or to coincidental infection with adenovirus and the agent of infectious hepatitis.
在50例急性黄疸型传染性肝炎患者的血清对（100%）中均发现了中和5型腺病毒的抗体。普通人群血清中的发生率为57%。对同一血清检测巨细胞病毒补体结合抗体和风疹病毒血凝素抗体时，在平均滴度或阳性血清比例方面未发现差异。这些结果可以解释为支持腺病毒直接或间接参与传染性肝炎的病因学；但也可能是由于对腺病毒抗体产生的非特异性回忆性增强，或者是由于腺病毒与传染性肝炎病原体的巧合感染。
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