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1
Activation of the peripheral lymphocytes in the course of the immune response to transplanted SV40-transformed tumour cells in hamsters.在仓鼠对移植的SV40转化肿瘤细胞的免疫反应过程中，外周淋巴细胞的激活。
Immunology. 1974 Jul;27(1):159-61.
2
Development in hamsters of antibodies against surface antigens present in cells transformed by papovavirus SV40.仓鼠体内针对由乳头瘤病毒SV40转化的细胞中存在的表面抗原的抗体的发育情况。
J Immunol. 1968 Feb;100(2):358-62.
3
Humoral and cellular immune response during the growth of an SV40 induced tumour in hamsters.仓鼠中SV40诱导肿瘤生长过程中的体液免疫和细胞免疫反应。
Ann Microbiol (Paris). 1977 Oct;128(3):385-98.
4
Evidence for tolerance to SV40 tumor antigen in hamsters bearing para-adenovirus 12 tumor transplants.携带副腺病毒12肿瘤移植瘤的仓鼠对SV40肿瘤抗原耐受性的证据。
J Immunol. 1970 Feb;104(2):305-11.
5
Cytotoxic action of spleen lymphocytes to simian virus 40-induced tumor cells.脾淋巴细胞对猿猴病毒40诱导的肿瘤细胞的细胞毒性作用。
Acta Med Okayama. 1973 Aug;27(3):107-23.
6
[Immunization of hamsters against tumors induced by the SV40 virus].[仓鼠针对SV40病毒诱导的肿瘤的免疫接种]
Arch Roum Pathol Exp Microbiol. 1970 Mar-Jun;29(1):109-16.
7
[Prevention of tumor growth by immunization of hamsters with x-irradiated SV40-transformed cells].[用X射线照射的SV40转化细胞免疫仓鼠预防肿瘤生长]
Harefuah. 1969 Nov 2;77(9):376-9.
8
[Comparative immunogenicity of irradiated and nonirradiated syngeneic and xenogeneic tumor cells containing a common specific transplantation antigen].[含有共同特异性移植抗原的经照射和未经照射的同基因及异种肿瘤细胞的比较免疫原性]
Biull Eksp Biol Med. 1978 Aug;86(8):225-8.
9
Prevention of SV40 virus oncogenesis in hamsters. II. The effect of thymectomy on induction of tumor resistance by SV40-transformed human cells.仓鼠中SV40病毒致癌作用的预防。II. 胸腺切除对SV40转化的人细胞诱导肿瘤抗性的影响。
J Immunol. 1967 Dec;99(6):1217-20.
10
[Formation of tumors from cells transformed in vitro by SV40 virus].[由SV40病毒体外转化的细胞形成肿瘤]
Vopr Onkol. 1970;16(1):63-9.

引用本文的文献

1
Lymphocyte nucleoli activation as a marker of autoimmune disorder development. I. Observation in NZB mice.淋巴细胞核仁激活作为自身免疫性疾病发展的标志物。I. 对新西兰黑小鼠的观察。
Immunology. 1976 Apr;30(4):475-7.
2
Lymphocyte nucleolar activation as a marker of autoimmune disorders. II. Observations in patients with systemic lupus erythematosus and other connective tissue diseases.淋巴细胞核仁激活作为自身免疫性疾病的标志物。II. 系统性红斑狼疮和其他结缔组织病患者的观察结果
Immunology. 1976 Nov;31(5):803-5.

本文引用的文献

1
A further contribution to the question of the incidence of nucleoli in the nuclei of mature lymphocytes in man.对人类成熟淋巴细胞细胞核中核仁发生率问题的进一步贡献。
Folia Biol (Praha). 1961;7:268-74.
2
In vitro correlates of transplantation immunity: the release of substances by immune lymphocytes confronted with specific antigens.移植免疫的体外相关因素：免疫淋巴细胞在接触特定抗原时释放物质。
Surgery. 1969 Jul;66(1):51-7.
3
Inflammatory lymphoid cells. Cells in immunized lymph nodes that move to sites of inflammation.炎性淋巴细胞。存在于免疫淋巴结中并迁移至炎症部位的细胞。
Immunology. 1972 Mar;22(3):493-502.
4
Demonstration of migration inhibiting substances in sera of guinea pigs with delayed type hypersensitivity to ovalbumin influenced with systemic antigen administration.对经全身抗原给药影响的、对卵清蛋白具有迟发型超敏反应的豚鼠血清中迁移抑制物质的证明。
Z Immunitatsforsch Allerg Klin Immunol. 1968 Aug-Sep;136(3):259-67.
5
A further contribution to the demonstration of RNA and nucleoli of blood cells in smear preparations.涂片制备中血细胞RNA和核仁显示的进一步贡献。
Folia Haematol Int Mag Klin Morphol Blutforsch. 1969;91(4):381-94.
6
Activation of peripheral lymphocytes in the course of experimental allergic encephalomyelitis in the guinea-pig.豚鼠实验性变应性脑脊髓炎过程中外周淋巴细胞的激活
Z Immunitatsforsch Exp Klin Immunol. 1972 Mar;143(2):139-46.

在仓鼠对移植的SV40转化肿瘤细胞的免疫反应过程中，外周淋巴细胞的激活。

Activation of the peripheral lymphocytes in the course of the immune response to transplanted SV40-transformed tumour cells in hamsters.

作者信息

Nekvasil M, Pekárek J

出版信息

Immunology. 1974 Jul;27(1):159-61.

PMID:4368371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1445590/
Abstract

Nucleolar changes were used to assess activated lymphocytes. About 10 per cent of peripheral lymphocytes in hamsters are activated by this criterion. This figure rises to 20–30 per cent following inoculation with SV40-transformed hamster cells. It reverts to normal or below at 3 weeks in those animals which develop macroscopic tumours but stays elevated in those animals which reject their tumours.

摘要

核仁变化被用于评估活化淋巴细胞。按照这一标准，仓鼠外周血淋巴细胞中约10%被激活。接种SV40转化的仓鼠细胞后，这一比例升至20% - 30%。在出现肉眼可见肿瘤的动物中，3周时该比例恢复正常或降至正常水平以下，但在排斥肿瘤的动物中仍保持升高。