小鼠仙台病毒感染的免疫反应和发病机制研究。II. 支气管粘膜下层浆细胞的免疫球蛋白类别
Studies on the immune response and pathogenesis of Sendai virus infection of mice. II. The immunoglobulin class of plasma cells in the bronchial sub-mucosa.
作者信息
Blandford G, Heath R B
出版信息
Immunology. 1974 Mar;26(3):667-71.
Abstract
The classes of immunoglobulin-containing cells in the lungs of mice after primary infection with Sendai virus were studied using an indirect immunofluorescence technique. It was found that during the first 5 days of the infection there was a considerable increase in all classes of immunoglobulin-containing cells with the IgA-containing cells retaining their pre-infection predominance. By the 6th day of the infection both IgG and IgA cells were present in equal numbers. This 1:1 ratio persisted for nearly 30 days and was followed by a gradual reversion to IgA excess. IgM-containing cells represented only 1/15–1/30 of all immunoglobulin-containing cells at any time during the infection.
摘要
利用间接免疫荧光技术研究了仙台病毒初次感染后小鼠肺中含免疫球蛋白细胞的类别。结果发现，在感染的前5天，所有含免疫球蛋白细胞的数量都有显著增加，其中含IgA的细胞保持了感染前的优势地位。到感染第6天，IgG细胞和IgA细胞数量相等。这种1:1的比例持续了近30天，随后逐渐恢复到IgA过量。在感染期间的任何时候，含IgM的细胞仅占所有含免疫球蛋白细胞的1/15 - 1/30。
相似文献
1
2
Immunoglobulin-containing cells in lungs of hamsters infected with Mycoplasma pneumoniae.感染肺炎支原体的仓鼠肺部含免疫球蛋白的细胞。
J Immunol. 1972 May;108(5):1400-8.
3
Studies of the immune respnse in Sendai virus infection of mice.小鼠仙台病毒感染中免疫反应的研究。
J Med Microbiol. 1971 Aug;4(3):351-6. doi: 10.1099/00222615-4-3-351.
4
Immunoglobulin class-specific antibody response in serum, spleen, lungs, and bronchoalveolar washings after primary and secondary sendai virus infection of germfree mice.无菌小鼠初次和二次感染仙台病毒后，血清、脾脏、肺脏和支气管肺泡灌洗液中的免疫球蛋白类特异性抗体反应。
Infect Immun. 1977 Sep;17(3):521-7. doi: 10.1128/iai.17.3.521-527.1977.
5
6
Immunofluorescent studies in patients with farmer's lung.对农民肺患者的免疫荧光研究。
J Allergy Clin Immunol. 1971 Oct;48(4):224-9. doi: 10.1016/0091-6749(71)90069-8.
7
Mice lacking CD8+ T cells develop greater numbers of IgA-producing cells in response to a respiratory virus infection.缺乏CD8+ T细胞的小鼠在应对呼吸道病毒感染时会产生更多数量的产生IgA的细胞。
Virology. 1994 Oct;204(1):234-41. doi: 10.1006/viro.1994.1527.
8
[Hyaline membrane disease. Immunofluorescent study. The role of complement].[透明膜病。免疫荧光研究。补体的作用]
Nouv Presse Med. 1974 Jun 22;3(25):1598-1602.
9
10
Immunoglobulin containing cells in the bronchopulmonary system of non-pneumonic and pneumonic calves.非肺炎和肺炎犊牛支气管肺系统中含免疫球蛋白的细胞。
Res Vet Sci. 1979 May;26(3):349-55.
引用本文的文献
1
Dynamics of Sendai Virus Spread, Clearance, and Immunotherapeutic Efficacy after Hematopoietic Cell Transplant Imaged Noninvasively in Mice.造血细胞移植后仙台病毒在小鼠体内传播、清除及免疫治疗效果的动态变化：无创成像研究
J Virol. 2018 Jan 2;92(2). doi: 10.1128/JVI.01705-17. Print 2018 Jan 15.
2
T cell memory in the lung airways.肺气道中的T细胞记忆
Proc Am Thorac Soc. 2005;2(2):126-31. doi: 10.1513/pats.200501-003AW.
3
Cellular immunity and memory to respiratory virus infections.对呼吸道病毒感染的细胞免疫和记忆
Immunol Res. 2001;24(1):53-67. doi: 10.1385/IR:24:1:53.
4
Genetics of natural resistance to Sendai virus infection in mice.小鼠对仙台病毒感染天然抗性的遗传学
Infect Immun. 1983 Jul;41(1):308-12. doi: 10.1128/iai.41.1.308-312.1983.
5
Sendai virus infection in genetically resistant and susceptible mice.仙台病毒在基因抗性和易感性小鼠中的感染
Am J Pathol. 1981 Nov;105(2):156-63.
6
Isotype commitment of B cells and dissemination of the primed state after mucosal stimulation with Mycoplasma pulmonis.肺炎支原体黏膜刺激后B细胞的同种型定向及致敏状态的扩散
Infect Immun. 1985 Aug;49(2):428-34. doi: 10.1128/iai.49.2.428-434.1985.
7
Immunological features of minor salivary gland saliva.小唾液腺唾液的免疫学特征
J Clin Immunol. 1987 Nov;7(6):449-55. doi: 10.1007/BF00915054.
8
Protection of mice from wild-type Sendai virus infection by a trypsin-resistant mutant, TR-2.通过一种抗胰蛋白酶突变体TR-2保护小鼠免受野生型仙台病毒感染。
J Virol. 1985 Jan;53(1):228-34. doi: 10.1128/JVI.53.1.228-234.1985.
9
Cell-mediated immunity induced in mice after vaccination with a protease activation mutant, TR-2, of Sendai virus.用仙台病毒的蛋白酶激活突变体TR-2对小鼠进行疫苗接种后诱导的细胞介导免疫。
J Virol. 1988 Jul;62(7):2490-7. doi: 10.1128/JVI.62.7.2490-2497.1988.
10
Protection of mice against virulent virus infection by a temperature-sensitive mutant derived from an HVJ (Sendai virus) carrier culture.源自HVJ（仙台病毒）载体培养物的温度敏感突变体对小鼠抵抗强毒病毒感染的保护作用。
Arch Virol. 1979;61(4):297-304. doi: 10.1007/BF01315016.
本文引用的文献
1
2
Studies of the immune respnse in Sendai virus infection of mice.小鼠仙台病毒感染中免疫反应的研究。
J Med Microbiol. 1971 Aug;4(3):351-6. doi: 10.1099/00222615-4-3-351.
3
The effect of cyclophosphamide on Sendai virus infection of mice.环磷酰胺对小鼠仙台病毒感染的影响。
J Med Microbiol. 1969 May;2(2):137-45. doi: 10.1099/00222615-2-2-137.
4
The pathogenesis of Sendai virus infection in the mouse lung.仙台病毒在小鼠肺部感染的发病机制。
J Med Microbiol. 1968 Aug;1(1):89-95. doi: 10.1099/00222615-1-1-89.
5
Arthus reaction and pneumonia.阿瑟氏反应与肺炎。
Br Med J. 1970 Mar 21;1(5698):758-9. doi: 10.1136/bmj.1.5698.758-d.
6
Secretory immunoglobulins.分泌型免疫球蛋白
Adv Immunol. 1968;9:1-96. doi: 10.1016/s0065-2776(08)60441-1.
Zotero 插件