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[神经营养药物对纹状体苍白球复合体结构兴奋性的影响]

[Effect of neurotropic drugs on the excitability of the structures of the striopallidal complex].

作者信息

Miasnikova E M

出版信息

Farmakol Toksikol. 1979 Mar-Apr;42(2):102-6.

PMID:437075
Abstract

The results of investigations into the effect of microinjections of a number of adrenocholino- and dophaminergic agents on excitability of the pale globe, caudate nucleus and shell are reported. The non-uniformity of the effects produced by the agents of the mediator type action is established both in different segments and in individual zones of the extrapyramidal system with continuous concurrent antagonism between the mimetics and the corresponding blocking agents. The presence of alpha- and beta-adrenoreceptors and also of M- and N-cholinoreceptors in the structures of the striopallidal complex is suggested.

摘要

本文报道了对多种肾上腺胆碱能和多巴胺能药物微量注射对苍白球、尾状核和壳核兴奋性影响的研究结果。在锥体外系的不同节段和各个区域,已证实具有介质类型作用的药物所产生的效应存在不均一性,同时拟似剂与相应阻断剂之间存在持续的拮抗作用。提示在纹状体苍白球复合体结构中存在α和β肾上腺素能受体以及M和N胆碱能受体。

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