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细胞培养中解离的大鼠交感神经元之间胆碱能突触的证据。

Evidence for cholinergic synapses between dissociated rat sympathetic neurons in cell culture.

作者信息

O'Lague P H, Obata K, Claude P, Furshpan E J, Potter D D

出版信息

Proc Natl Acad Sci U S A. 1974 Sep;71(9):3602-6. doi: 10.1073/pnas.71.9.3602.

Abstract

Sympathetic principal neurons were dissociated from superior cervical ganglia of new-born rats, and grown in cell culture. In electrophysiological experiments two types of excitatory synapses were found. One, which was relatively rare, was shown to operate by electrical transmission. The other, the predominant type, had several characteristics of chemical transmission, and pharmacological evidence indicated it was cholinergic.

摘要

从新生大鼠的颈上神经节分离出交感神经主神经元,并在细胞培养中生长。在电生理实验中发现了两种类型的兴奋性突触。一种相对罕见,显示通过电传递起作用。另一种是主要类型,具有化学传递的几个特征,药理学证据表明它是胆碱能的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/759b/433823/58978e50ac8a/pnas00072-0289-a.jpg

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