还原当量在黄嘌呤氧化酶分子上的分布以及分子内电子转移反应的速率。
Distribution of reducing equivalents on xanthine oxidase molecules and the rates of the intramolecular electron-transfer reactions.
作者信息
Bray R C, Lowe D J, Barber M J
出版信息
Biochem J. 1974 Jul;141(1):309-11. doi: 10.1042/bj1410309.
Abstract
When xanthine oxidase turns over 1-methylxanthine aerobically at pH8.2, the time-sequence in development of its electron-paramagnetic-resonance signals is not primarily due to slow intramolecular reactions among its centres. It derives instead from gross differences in electron distribution within enzyme molecules reduced by the substrate in comparison with those that have subsequently been partly reoxidized by one-electron reaction with oxygen.
摘要
当黄嘌呤氧化酶在pH8.2的条件下有氧氧化1-甲基黄嘌呤时，其电子顺磁共振信号发展的时间序列并非主要源于其中心之间缓慢的分子内反应。相反，它源于与随后通过与氧的单电子反应而部分再氧化的酶分子相比，被底物还原的酶分子内电子分布的显著差异。
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Distribution of reducing equivalents on xanthine oxidase molecules and the rates of the intramolecular electron-transfer reactions.还原当量在黄嘌呤氧化酶分子上的分布以及分子内电子转移反应的速率。
Biochem J. 1974 Jul;141(1):309-11. doi: 10.1042/bj1410309.
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Sudden freezing as a technique for the study of rapid reactions.骤冷法作为一种研究快速反应的技术。
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Magnetic and spectrophotometric studies of the kinetics of the catalysis of xanthine oxidation by xanthine oxidase from cow's milk.牛奶中黄嘌呤氧化酶催化黄嘌呤氧化动力学的磁性和分光光度研究。
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Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase.牛奶黄嘌呤氧化酶产生超氧阴离子自由基的定量研究。
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Studies by electron paramagnetic resonance on the catalytic mechanism of nitrogenase of Klebsiella pneumoniae.肺炎克雷伯菌固氮酶催化机制的电子顺磁共振研究。
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Kinetic studies on the substrate reduction of xanthine oxidase.黄嘌呤氧化酶底物还原的动力学研究。
J Biol Chem. 1973 Sep 10;248(17):6135-44.
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Spin-spin interaction between molybdenum and one of the iron-sulphur systems of xanthine oxidase and its relevance to the enzymic mechanism.钼与黄嘌呤氧化酶的铁硫系统之一之间的自旋-自旋相互作用及其与酶促机制的相关性。
Biochem J. 1972 Nov;130(1):239-49. doi: 10.1042/bj1300239.
9
Multiple phases in the reduction of xanthine oxidase by substrates.底物还原黄嘌呤氧化酶的多个阶段。
Eur J Biochem. 1972 Apr 11;26(3):407-15. doi: 10.1111/j.1432-1033.1972.tb01781.x.
10
The existence of nonfunctional active sites in milk xanthine oxidase: reaction with functional active site inhibitors.牛奶黄嘌呤氧化酶中无功能活性位点的存在：与功能活性位点抑制剂的反应
Vitam Horm. 1970;28:505-31. doi: 10.1016/s0083-6729(08)60909-7.
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