Szpakowicz T, Boron P, Borzuchowska A, Prokopowicz D, Bobrowska E, Kaczmarska A, Pytel B, Rzewnicki I
Infection. 1979;7(2):57-60. doi: 10.1007/BF01641613.
The level of serotonin in blood, the activity of MAO in serum and the value of 5-HIAA in 24 hour urine were estimated in 76 patients with viral hepatitis divided according to clinical parameters into three groups (mild, mild to severe and severe clinical course). A statistically significant increase of serotonin level in blood compared with the healthy control group was found. Highest values were observed in patients with the severe form of viral hepatitis. Decreased values of 5-HIAA in 24 hour urine in the early course of the disease showed a tendency to increase in later examinations. The activity of MAO in serum was significantly lowered in all clinical forms of viral hepatitis.
对76例病毒性肝炎患者进行了血液中血清素水平、血清中MAO活性及24小时尿中5 - HIAA值的测定。根据临床参数将这些患者分为三组（轻度、轻至重度和重度病程）。结果发现，与健康对照组相比，血液中血清素水平有统计学意义的升高。在重型病毒性肝炎患者中观察到最高值。疾病早期24小时尿中5 - HIAA值降低，在后期检查中有升高趋势。在病毒性肝炎的所有临床类型中，血清中MAO活性均显著降低。
