δ-5,7,24-胆甾三烯-3β-醇及其他天然存在的甾醇的酶促合成途径以及向胆固醇的转化 - Suppr

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超能文献

Pathways of enzymic synthesis and conversion to cholesterol of delta-5,7,24-cholestatrien-3 beta-ol and other naturally occurring sterols.

作者信息

Dempsey M E

出版信息

J Biol Chem. 1965 Nov;240(11):4176-88.

PMID:4378934

Abstract

摘要

相似文献

Pathways of enzymic synthesis and conversion to cholesterol of delta-5,7,24-cholestatrien-3 beta-ol and other naturally occurring sterols.δ-5,7,24-胆甾三烯-3β-醇及其他天然存在的甾醇的酶促合成途径以及向胆固醇的转化

J Biol Chem. 1965 Nov;240(11):4176-88.

Conversion of beta sitosterol to cholesterol blocked in an insect by hypocholesterolemic agents.在昆虫体内，β-谷甾醇向胆固醇的转化被降胆固醇药物阻断。

Science. 1967 Jun 23;156(3782):1637-8. doi: 10.1126/science.156.3782.1637.

Synthesis of delta 5,22-cholestadien-3 beta-ol from delta 5,7,22-cholestatrien-3 beta-ol by a liver enzyme.肝脏酶催化从Δ5,7,22-胆甾三烯-3β-醇合成Δ5,22-胆甾二烯-3β-醇。

Lipids. 1981 Oct;16(10):755-8. doi: 10.1007/BF02535344.

Agents affecting lipid metabolism. 28. A 7-dehydrocholesterol delta-7-reductase inhibitor (AY-9944) as tool in studies of delta-7-sterol metabolism.影响脂质代谢的药物。28. 一种7-脱氢胆固醇δ-7-还原酶抑制剂（AY-9944）作为δ-7-甾醇代谢研究的工具。

Biochemistry. 1966 Mar;5(3):1060-4. doi: 10.1021/bi00867a035.

Effect of hypocholesterolemic agents on central nervous system cholesterol biosynthesis III. Zuclomiphene in combination with AY9944 and triparanol.降胆固醇药物对中枢神经系统胆固醇生物合成的影响III. 氯米芬与AY9944及曲帕拉醇联合使用的情况

Biochem Pharmacol. 1978;27(12):1637-40. doi: 10.1016/0006-2952(78)90172-7.

Measurement of the absolute rates of cholesterol biosynthesis in isolated rat liver cells.分离的大鼠肝细胞中胆固醇生物合成绝对速率的测定。

Biochem J. 1977 Feb 15;162(2):321-30. doi: 10.1042/bj1620321.

Enzymatic conversion of delta8, 14-cholestadien-3beta-ol to cholesterol.将δ8,14-胆甾二烯-3β-醇酶促转化为胆固醇。

Biochem Biophys Res Commun. 1968 Nov 8;33(3):492-6. doi: 10.1016/0006-291x(68)90602-5.

Inhibition of cholesterol synthesis and cell growth by 24(R,S),25-iminolanosterol and triparanol in cultured rat hepatoma cells.24（R，S），25-亚氨基羊毛甾醇和曲帕拉醇对培养的大鼠肝癌细胞胆固醇合成及细胞生长的抑制作用

J Biol Chem. 1989 Apr 15;264(11):6230-8.

In vivo demonstration of the cholesterol feedback system by means of a desmosterol suppression technique.通过去氢胆固醇抑制技术对胆固醇反馈系统进行体内验证。

J Clin Invest. 1972 Feb;51(2):197-205. doi: 10.1172/JCI106804.

Enzymatic conversion of delta-8(14)-cholesten-3-beta-ol to cholesterol.δ-8(14)-胆甾烯-3-β-醇向胆固醇的酶促转化。

Biochem Biophys Res Commun. 1968 Aug 21;32(4):635-8. doi: 10.1016/0006-291x(68)90285-4.

引用本文的文献

The conversion of cholest-7-en-3beta-ol into cholesterol. General comments on the mechanism of the introduction of double bonds in enzymic reactions.胆甾-7-烯-3β-醇转变为胆固醇。关于酶反应中双键引入机制的一般评述。

Biochem J. 1967 Dec;105(3):1187-94. doi: 10.1042/bj1051187.

Purification, molecular cloning, and expression of the mammalian sigma1-binding site.哺乳动物σ1结合位点的纯化、分子克隆及表达

Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):8072-7. doi: 10.1073/pnas.93.15.8072.

Sterol metabolism and oral epithelial cell growth.甾醇代谢与口腔上皮细胞生长。

In Vitro Cell Dev Biol Anim. 1993 Sep;29A(9):693-8. doi: 10.1007/BF02631425.

Synthesis of delta 5,22-cholestadien-3 beta-ol from delta 5,7,22-cholestatrien-3 beta-ol by a liver enzyme.肝脏酶催化从Δ5,7,22-胆甾三烯-3β-醇合成Δ5,22-胆甾二烯-3β-醇。

Lipids. 1981 Oct;16(10):755-8. doi: 10.1007/BF02535344.

The stereochemistry of the hydrogen elimination in the biological conversion of cholest-7-en-3-beta-ol into cholesterol.胆甾-7-烯-3-β-醇生物转化为胆固醇过程中氢消除的立体化学。

Biochem J. 1967 Feb;102(2):462-7. doi: 10.1042/bj1020462.

Cholesterol requirement of primary diploid human fibroblasts.原代二倍体人成纤维细胞的胆固醇需求

J Cell Biol. 1969 Jul;42(1):262-71. doi: 10.1083/jcb.42.1.262.

The role of a cholesta-8,14-dien-3-beta-ol system in cholesterol biosynthesis.胆甾-8,14-二烯-3-β-醇系统在胆固醇生物合成中的作用。

Biochem J. 1969 Mar;111(5):757-61. doi: 10.1042/bj1110757.

The mechanism of the elaboration of ring B in ergosterol biosynthesis.麦角固醇生物合成中B环形成的机制。

Biochem J. 1968 Jul;108(4):527-31. doi: 10.1042/bj1080527.

Metabolism of lathosterol by Drosophila pachea.果蝇帕切亚对羊毛甾醇的代谢

Lipids. 1971 Mar;6(3):166-9. doi: 10.1007/BF02533031.

Incorporation of (2-14C, (5r)-5-3H1) mevalonic acid into cholesterol by a rat liver homogenate and into beta-sitosterol and 28-isofucosterol by larix decidua leaves.大鼠肝脏匀浆将（2-¹⁴C，（5r）-5-³H¹）甲羟戊酸掺入胆固醇中，落叶松叶片将其掺入β-谷甾醇和28-异岩藻甾醇中。

Biochem J. 1969 Oct;114(4):885-92. doi: 10.1042/bj1140885.

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