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肺炎球菌和链球菌中影响生长速率及对链霉素抗性的突变之间的相互作用

Interaction of mutations affecting growth rate and resistance to streptomycin in pneumococci and streptococci.

作者信息

Krauss M R, King J C, Cox R P

出版信息

J Bacteriol. 1966 Nov;92(5):1337-44. doi: 10.1128/jb.92.5.1337-1344.1966.

Abstract

Krauss, Marjorie R. (New York University Medical Center, New York, N.Y.), James C. King, and Rody P. Cox. Interaction of mutations affecting growth rate and resistance to streptomycin in pneumococci and streptococci. J. Bacteriol. 92:1337-1344. 1966.-A strain of Streptococcus (Viridans group) was shown by transformation reactions to be the carrier of two interacting mutations. One produced resistance to streptomycin and a slow rate of growth; the only effect of the second was an increase in growth rate when it was added by transformation to streptococcal strains that had already been transformed to bear the first. Similar modifying mutations were observed in strains of streptococci and pneumococci into which the first mutation had been introduced by transformation.

摘要

克劳斯,玛乔丽·R.(纽约大学医学中心,纽约州纽约市),詹姆斯·C.金,以及罗迪·P.考克斯。肺炎球菌和链球菌中影响生长速率及对链霉素抗性的突变之间的相互作用。《细菌学杂志》92:1337 - 1344。1966年。——通过转化反应表明,一株链球菌(草绿色链球菌群)是两个相互作用突变的携带者。一个突变产生对链霉素的抗性和缓慢的生长速率;第二个突变的唯一作用是,当通过转化将其添加到已经转化为携带第一个突变的链球菌菌株中时,会提高生长速率。在通过转化引入了第一个突变的链球菌和肺炎球菌菌株中也观察到了类似的修饰突变。

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