Smith R G
Science. 1967 Feb 3;155(3762):603-5. doi: 10.1126/science.155.3762.603.
Either a placebo or 25 or 37.5 milligrams of magnesium pemoline was administered on a doubleblind basis to three intelligencematched groups of normal, adult males. Learning and 24-hour retention tests included verbal learning, motor learning, and classical conditioning. Short-term memory tests were administered through both the visual and auditory modalities. Arm-hand steadiness and visual reaction time performance tests were included. The only measures revealing significant group differences showed the performance of subjects given pemoline was inferior to that of subjects given a placebo.
在双盲的基础上,给三组智力匹配的正常成年男性分别服用安慰剂、25毫克或37.5毫克的匹莫林。学习和24小时记忆测试包括言语学习、运动学习和经典条件反射。短期记忆测试通过视觉和听觉两种方式进行。还包括手臂手部稳定性和视觉反应时间性能测试。唯一显示出显著组间差异的测量结果表明,服用匹莫林的受试者的表现不如服用安慰剂的受试者。