Uitto J, Santa-Cruz D J, Eisen A Z, Kobayashi G S
J Cutan Pathol. 1979 Feb;6(1):77-84. doi: 10.1111/j.1600-0560.1979.tb00308.x.
A case of chromomycosis, caused by Fonsecaea pedrosoi, was treated with 5-fluorocytosine. After 18 weeks of treatment the initial lesions had largely resolved, and no evidence of active disease was observed clinically, histologically or from fungal cultures of the biopsy material. Further resolution of the remaining hypertrophic scar was achieved by intralesional injections of triamcinolone acetonide. Minimal side-effects were encountered during the therapy, and no recurrence during an 18-month follow-up period was observed. The results of this study indicate that 5-fluorocytosine is an effective and relatively safe mode of therapy in chromomycosis.
1例由裴氏瓶霉引起的着色芽生菌病患者接受了5-氟胞嘧啶治疗。治疗18周后，初始皮损已基本消退，临床、组织学检查或活检材料真菌培养均未发现活动性疾病迹象。通过病灶内注射曲安奈德，剩余的肥厚性瘢痕进一步消退。治疗期间出现的副作用极小，在18个月的随访期内未观察到复发。本研究结果表明，5-氟胞嘧啶是治疗着色芽生菌病的一种有效且相对安全的治疗方式。
