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Requirement of NADPH and molecular oxygen for the side-chain cleavage of 20-alpha, 22-xi-dihydroxycholesterol.

作者信息

Shimizu K

出版信息

Arch Biochem Biophys. 1968 Jun;125(3):1016-7. doi: 10.1016/0003-9861(68)90539-0.

DOI:10.1016/0003-9861(68)90539-0
PMID:4386446
Abstract
摘要

相似文献

1
Requirement of NADPH and molecular oxygen for the side-chain cleavage of 20-alpha, 22-xi-dihydroxycholesterol.
Arch Biochem Biophys. 1968 Jun;125(3):1016-7. doi: 10.1016/0003-9861(68)90539-0.
2
Sterol metabolism. 8. Conversion of cholesterol 20 alpha-hydroperoxide to 20 alpha, 21- and 20 alpha, 22R-dihydroxycholesterol by adrenal cortex mitochondria.
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A possible role for transhydrogenation in side-chain cleavage of cholesterol.转氢作用在胆固醇侧链裂解中的可能作用。
Biochemistry. 1972 Jul 18;11(15):2891-7. doi: 10.1021/bi00765a023.
4
Electron transport in relation to steroid biosynthesis. Inhibition of side-chain cleavage of cholesterol by hyperbaric oxygen.
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Isotope-Labeling Studies Support the Electrophilic Compound I Iron Active Species, FeO(3+), for the Carbon-Carbon Bond Cleavage Reaction of the Cholesterol Side-Chain Cleavage Enzyme, Cytochrome P450 11A1.同位素标记研究支持亲电化合物 I 铁活性物种 FeO(3+) 用于胆固醇侧链裂解酶细胞色素 P450 11A1 的碳-碳键断裂反应。
J Am Chem Soc. 2016 Sep 21;138(37):12124-41. doi: 10.1021/jacs.6b04437. Epub 2016 Sep 12.
6
Mechanism of cholesterol side-chain cleavage. II. The enzymic hydroperoxide-glycol rearrangement of the epimeric 20-hydroperxycholesterols in 18O-enriched water.胆固醇侧链裂解的机制。II. 在富含18O的水中,差向异构的20-氢过氧胆固醇的酶促氢过氧化物-二醇重排反应
Biochim Biophys Acta. 1977 May 25;487(2):395-9. doi: 10.1016/0005-2760(77)90016-9.
7
Kinetic studies on substrate-enzyme interaction in the adrenal cholesterol side-chain cleavage system.
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8
Assay of microsomal oxysterol 7alpha-hydroxylase activity in the hamster liver by a sensitive method: in vitro modulation by oxysterols.
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9
Electron leakage from the mitochondrial NADPH-adrenodoxin reductase-adrenodoxin-P450scc (cholesterol side chain cleavage) system.线粒体烟酰胺腺嘌呤二核苷酸磷酸-肾上腺皮质铁氧化还原蛋白还原酶-肾上腺皮质铁氧化还原蛋白-胆固醇侧链裂解酶(P450scc)系统的电子泄漏
Arch Biochem Biophys. 1993 Sep;305(2):489-98. doi: 10.1006/abbi.1993.1452.
10
[Molecular mechanism of enzymic cleavage of cholesterol side chain (author's transl)].胆固醇侧链酶促裂解的分子机制(作者译)
Seikagaku. 1977 Feb;49(2):76-84.

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Enzymes of ecdysteroid transformation and inactivation in the midgut of the cotton leafworm, Spodoptera littoralis: properties and developmental profiles.棉铃虫(Spodoptera littoralis)中肠内蜕皮甾体转化和失活的酶:特性及发育概况
Biochem J. 1995 Dec 1;312 ( Pt 2)(Pt 2):561-8. doi: 10.1042/bj3120561.
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The stoichiometry of the conversion of cholesterol and hydroxycholesterols to pregnenolone (3beta-hydroxypregn-5-en-20-one) catalysed by adrenal cytochrome P-450.肾上腺细胞色素P-450催化胆固醇和羟基胆固醇转化为孕烯醇酮(3β-羟基孕-5-烯-20-酮)的化学计量关系。
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1441-5. doi: 10.1073/pnas.71.4.1441.