组胺拮抗剂对缓激肽诱导的血管通透性增加的抑制作用。
Inhibition by antihistamines of the vascular permeability increase induced by bradykinin.
作者信息
Becker E L, Mota I, Wong D
出版信息
Br J Pharmacol. 1968 Oct;34(2):330-6. doi: 10.1111/j.1476-5381.1968.tb07054.x.
Abstract
- Mepyramine and triprolidine hydrochloride have a marked inhibitory effect on the local increase of vascular permeability induced by bradykinin.2. The anti-bradykinin effect of both antihistamines was species dependent, being evident in rabbits, rats and mice but not in guinea-pigs.
摘要
美吡拉敏和盐酸曲普利啶对缓激肽诱导的局部血管通透性增加有显著抑制作用。
两种抗组胺药的抗缓激肽作用具有种属依赖性，在兔、大鼠和小鼠中明显，但在豚鼠中不明显。
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本文引用的文献
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The role of histamine and bradykinin in the inflammatory process.组胺和缓激肽在炎症过程中的作用。
Arch Int Pharmacodyn Ther. 1962 Dec 1;140:528-38.
2
A comparative study of kinin, kallidin, and bradykinin.激肽、胰激肽和缓激肽的比较研究。
Br J Pharmacol Chemother. 1957 Jun;12(2):149-58. doi: 10.1111/j.1476-5381.1957.tb00113.x.
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Responses of skin blood vessels to bradykinin, histamine and 5-hydroxytryptamine.皮肤血管对缓激肽、组胺和5-羟色胺的反应。
J Physiol. 1967 Nov;193(2):255-67. doi: 10.1113/jphysiol.1967.sp008356.
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Rabbit anaphylactic antibody.兔过敏抗体。
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