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组胺拮抗剂对缓激肽诱导的血管通透性增加的抑制作用。

Inhibition by antihistamines of the vascular permeability increase induced by bradykinin.

作者信息

Becker E L, Mota I, Wong D

出版信息

Br J Pharmacol. 1968 Oct;34(2):330-6. doi: 10.1111/j.1476-5381.1968.tb07054.x.

DOI:10.1111/j.1476-5381.1968.tb07054.x
PMID:4386856
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1703335/
Abstract
  1. Mepyramine and triprolidine hydrochloride have a marked inhibitory effect on the local increase of vascular permeability induced by bradykinin.2. The anti-bradykinin effect of both antihistamines was species dependent, being evident in rabbits, rats and mice but not in guinea-pigs.
摘要

  1. 美吡拉敏和盐酸曲普利啶对缓激肽诱导的局部血管通透性增加有显著抑制作用。

  2. 两种抗组胺药的抗缓激肽作用具有种属依赖性，在兔、大鼠和小鼠中明显，但在豚鼠中不明显。

相似文献

1
Inhibition by antihistamines of the vascular permeability increase induced by bradykinin.组胺拮抗剂对缓激肽诱导的血管通透性增加的抑制作用。
Br J Pharmacol. 1968 Oct;34(2):330-6. doi: 10.1111/j.1476-5381.1968.tb07054.x.
2
The effect of anti-inflammatory drugs on increased vascular permeability induced by chemical mediators.抗炎药物对化学介质诱导的血管通透性增加的影响。
J Pathol. 1972 Sep;108(1):1-14. doi: 10.1002/path.1711080102.
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[Energetic aspects of the effect of histamine and bradykinin on vascular permeability].[组胺和缓激肽对血管通透性影响的能量学方面]
Biull Eksp Biol Med. 1974 Oct;78(10):18-20.
4
The mechanism of blood vessel permeability derangement under the influence of histamine, serotonin and bradykinin.组胺、5-羟色胺和缓激肽影响下血管通透性紊乱的机制。
Experientia. 1970 Aug 15;26(8):843-4. doi: 10.1007/BF02114211.
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Effect of azelastine hydrochloride on vascular permeability in hypersensitivity reaction skin site in guinea pig.盐酸氮卓斯汀对豚鼠超敏反应皮肤部位血管通透性的影响。
Arzneimittelforschung. 1981;31(8):1212-5.
6
[Antibradykinin effect of dimedrol].[苯海拉明的抗缓激肽作用]
Farmakol Toksikol. 1967 May-Jun;30(3):321-4.
7
[Effect of antihistaminics on bradykinin action].[抗组胺药对缓激肽作用的影响]
Biull Eksp Biol Med. 1979 Oct;88(10):419-21.
8
The effects of oestrogens on bluing lesions by bradykinin and histamine.
Acta Endocrinol (Copenh). 1969 Feb;60(2):177-83. doi: 10.1530/acta.0.0600177.
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[Effect of drugs to the reaction experimentally induced by passive cutaneous anaphylaxis, bradykinin, histamine and serotonin].[药物对被动皮肤过敏反应、缓激肽、组胺和5-羟色胺所致实验性反应的作用]
Arerugi. 1969 Jun;18(6):530-3.
10
An antihistamine compound with potent antibradykinin activity.一种具有强效抗缓激肽活性的抗组胺化合物。
J Pharm Pharmacol. 1969 Aug;21(8):544-5. doi: 10.1111/j.2042-7158.1969.tb08310.x.

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Peanuts can contribute to anaphylactic shock by activating complement.花生可通过激活补体导致过敏性休克。
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Human reagins: appraisal of the properties of the antibody of immediate-type hypersensitivity.人反应素：速发型超敏反应抗体特性的评估
Bacteriol Rev. 1972 Sep;36(3):311-60. doi: 10.1128/br.36.3.311-360.1972.
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Heterogeneity of guinea-pig homocytotropic antibodies.豚鼠亲同种细胞抗体的异质性。
Immunology. 1972 May;22(5):915-23.
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Increased vascular permeability produced by human platelet granule cationic extract.人血小板颗粒阳离子提取物产生的血管通透性增加
J Clin Invest. 1970 Feb;49(2):274-81. doi: 10.1172/JCI106237.
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Passive cutaneous anaphylaxis in the rat, induced with two homologous reagin-like antibodies and its specific inhibition with disodium cromoglycate.用两种同源的类反应素抗体诱导大鼠被动皮肤过敏反应及其用色甘酸二钠的特异性抑制作用。
Immunology. 1969 Jun;16(6):749-60.
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Rabbit homocytotropic antibody. A unique rabbit immunoglobulin analogous to human IgE.兔亲同种细胞抗体。一种类似于人IgE的独特兔免疫球蛋白。
J Exp Med. 1969 Oct 1;130(4):907-29. doi: 10.1084/jem.130.4.907.
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Haemorrhagic and permeability increasing effects of 'Bothrops jararaca' and other Crotalidae venoms as related to amine or kinin release.
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Mediators of the inflammation induced in the rat paw by carrageenin.角叉菜胶诱导大鼠爪部炎症的介质。
Br J Pharmacol. 1971 Jul;42(3):392-402. doi: 10.1111/j.1476-5381.1971.tb07124.x.
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Homologous passive cutaneous anaphylaxis (PCA) in mice and heterologous PCA induced in rats with mouse IgE.小鼠的同种被动皮肤过敏反应（PCA）以及用小鼠IgE诱导大鼠产生的异种PCA。
Immunology. 1976 May;30(5):655-69.
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Histamine H1- and H2- receptor antagonists reduce histamine-induced increases in vascular permeability and oedema formation in cat skeletal muscle.组胺H1和H2受体拮抗剂可降低组胺诱导的猫骨骼肌血管通透性增加和水肿形成。
Agents Actions. 1979 Dec;9(5-6):450-4. doi: 10.1007/BF01968109.

本文引用的文献

1
The role of histamine and bradykinin in the inflammatory process.组胺和缓激肽在炎症过程中的作用。
Arch Int Pharmacodyn Ther. 1962 Dec 1;140:528-38.
2
A comparative study of kinin, kallidin, and bradykinin.激肽、胰激肽和缓激肽的比较研究。
Br J Pharmacol Chemother. 1957 Jun;12(2):149-58. doi: 10.1111/j.1476-5381.1957.tb00113.x.
3
Responses of skin blood vessels to bradykinin, histamine and 5-hydroxytryptamine.皮肤血管对缓激肽、组胺和5-羟色胺的反应。
J Physiol. 1967 Nov;193(2):255-67. doi: 10.1113/jphysiol.1967.sp008356.
4
Rabbit anaphylactic antibody.兔过敏抗体。
J Exp Med. 1966 May 1;123(5):935-50. doi: 10.1084/jem.123.5.935.
5
Effect of drugs on mast cells.药物对肥大细胞的作用。
Adv Pharmacol (1962). 1967;5:47-78. doi: 10.1016/s1054-3589(08)60654-7.