Leprohon C E, Woodger T L, Ashley D V, Anderson G H
J Nutr. 1979 May;109(5):827-31. doi: 10.1093/jn/109.5.827.
Weanling rats fed a choice of two diets varying only in protein concentration (10 and 60% casein) select a lower proportion of dietary energy as protein when the dietary minerals are supplied by a mineral mixture high in Na, K, and Cl but low in P and Cu (Hi Cl) than when the diets contain the Bernhart-Tomarelli (BT) mineral mixture. The addition of Na and/or K as acetate salts to the BT mineral mixture, to levels in the Hi Cl mixture, had no effect on regulation of protein intake. However, the addition of Na and/or K as chloride salts to the BT mineral mixture resulted in the rats selecting a protein concentration equivalent to the Hi Cl fed group. Weight gains and energy consumption were similar for all groups. It was therefore concluded that dietary chloride affects protein feeding behavior.
给断奶大鼠提供两种仅蛋白质浓度不同（10%和60%酪蛋白）的日粮供其选择，当日粮矿物质由钠、钾和氯含量高但磷和铜含量低的矿物质混合物（高氯）提供时，与日粮含有伯恩哈特 - 托马雷利（BT）矿物质混合物相比，大鼠选择的日粮能量中蛋白质的比例更低。向BT矿物质混合物中添加乙酸盐形式的钠和/或钾，使其达到高氯混合物中的水平，对蛋白质摄入量的调节没有影响。然而，向BT矿物质混合物中添加氯化物形式的钠和/或钾，导致大鼠选择的蛋白质浓度与喂食高氯组相当。所有组的体重增加和能量消耗相似。因此得出结论，日粮中的氯化物会影响蛋白质摄食行为。
