华法林剂量需求的可预测性：理论考量
Predictability of warfarin dose requirements: theoretical considerations.
作者信息
Sawyer W T
出版信息
J Pharm Sci. 1979 Apr;68(4):432-4. doi: 10.1002/jps.2600680410.
PMID:438962
Abstract
The theoretical basis of the predictability of warfarin maintenance dose requirements was evaluated using computer-generated hypothetical patient responses to a 10-mg/day "loading" dose regimen. Correlations between these responses and projected maintenance dose requirements were evaluated statistically, and a significant relationship was identified.
摘要
使用计算机生成的对每日10毫克“负荷”剂量方案的假设患者反应，评估了华法林维持剂量需求可预测性的理论基础。对这些反应与预计维持剂量需求之间的相关性进行了统计学评估，并确定了显著关系。
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