Bargo E
J Pharm Sci. 1979 Apr;68(4):503-5. doi: 10.1002/jps.2600680430.
A rapid, sensitive, and specific GLC method for the quantitation of trihexyphenidyl hydrochloride in various pharmaceutical dosage forms is described. The procedure involves chloroform extraction of the active ingredient from a weakly acidic solution, followed by GLC determination using a 3% methyl silicone column. The specificity of the system in relation to several compendial drug analogs also is reported.
描述了一种快速、灵敏且特异的气相色谱（GLC）方法，用于定量测定各种药物剂型中的盐酸苯海索。该方法包括从弱酸性溶液中用氯仿萃取活性成分，然后使用3%甲基硅氧烷柱进行气相色谱测定。还报告了该系统相对于几种药典药物类似物的特异性。
