Popp F D, Donigan B E
J Pharm Sci. 1979 Apr;68(4):519-20. doi: 10.1002/jps.2600680437.
Substituted isatins and substituted acetophenones were condensed to give analogs of 3-hydroxy-3-phenacyloxindole. These alcohols were dehydrated, and the alkene was reduced. None of the products had the level of anticonvulsant activity exhibited by the parent compound.
将取代异吲哚酮和取代苯乙酮缩合，得到3-羟基-3-苯乙酰基羟吲哚类似物。这些醇被脱水，烯烃被还原。没有一种产物具有母体化合物所表现出的抗惊厥活性水平。
