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Metabolism of cyclophosphamide by rat hepatic microsomes.

作者信息

Sladek N E

出版信息

Cancer Res. 1971 Jun;31(6):901-8.

PMID:4397323
Abstract
摘要

相似文献

1
Metabolism of cyclophosphamide by rat hepatic microsomes.大鼠肝微粒体对环磷酰胺的代谢
Cancer Res. 1971 Jun;31(6):901-8.
2
On the loss of reduced and oxidised nicotinamide adenine dinucleotide phosphate added to suspensions of rat liver.关于添加到大鼠肝脏悬液中的还原型和氧化型烟酰胺腺嘌呤二核苷酸磷酸的损失
Enzymologia. 1970 Sep 30;39(3):183-92.
3
In vitro activation of isophosphamide (NSC-109724), a new oxazaphosphorine, by rat liver microsomes.大鼠肝微粒体对新型恶唑磷（异环磷酰胺，NSC - 109724）的体外激活作用。
Cancer Chemother Rep. 1972 Oct;56(5):603-10.
4
Microsomal electron transport reactions. II. The use of reduced triphosphopyridine nucleotide and-or reduced diphosphopyridine nucleotide for the oxidative N-demethylation of aminopyrine and other drug substrates.
Arch Biochem Biophys. 1971 Mar;143(1):46-53. doi: 10.1016/0003-9861(71)90184-6.
5
Two-substrate kinetics of drug-metabolizing enzyme systems of hepatic microsomes.肝微粒体药物代谢酶系统的双底物动力学
Mol Pharmacol. 1970 May;6(3):206-12.
6
Hyperthermic modification of cyclophosphamide metabolism in rat hepatic microsomes and liver slices.大鼠肝微粒体和肝切片中环磷酰胺代谢的热修饰
Life Sci. 1981 Mar 9;28(10):1133-7. doi: 10.1016/0024-3205(81)90690-1.
7
Metabolism and binding of cyclophosphamide and its metabolite acrolein to rat hepatic microsomal cytochrome P-450.环磷酰胺及其代谢产物丙烯醛与大鼠肝微粒体细胞色素P-450的代谢及结合
Cancer Res. 1984 Oct;44(10):4615-21.
8
[Embryotoxic effect of cyclophosphamide after being biotransformed in a culture of postimplantation rat embryos].[环磷酰胺在植入后大鼠胚胎培养物中生物转化后的胚胎毒性作用]
Biull Eksp Biol Med. 1981 May;91(5):613-5.
9
The effect of starvation on the kinetics of drug oxidation by hepatic microsomal enzymes from male and female rats.饥饿对雄性和雌性大鼠肝脏微粒体酶药物氧化动力学的影响。
J Pharmacol Exp Ther. 1970 Oct;175(1):12-21.
10
Sulfoxide reduction: in vitro reduction of oxyprothepine-8-sulfoxide by rat hepatic cytosolic and microsomal enzymes.
Pharmazie. 1993 Oct;48(10):784-5.

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Probucol attenuates cyclophosphamide-induced oxidative apoptosis, p53 and Bax signal expression in rat cardiac tissues.普罗布考减轻环磷酰胺诱导的大鼠心肌组织氧化凋亡及 p53、Bax 信号表达。
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In vitro chromosome aberration tests using human dental pulp cells to detect the carcinogenic potential of chemical agents.利用人牙髓细胞进行体外染色体畸变试验以检测化学制剂的致癌潜力。
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High-dose ifosfamide, carboplatin, and etoposide pharmacokinetics: correlation of plasma drug levels with renal toxicity.大剂量异环磷酰胺、卡铂和依托泊苷的药代动力学：血浆药物水平与肾毒性的相关性
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Dose-dependent pharmacokinetics and cancer chemotherapy.剂量依赖性药代动力学与癌症化疗
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A bioassay for cyclophosphamide in blood, lung and tumour.血液、肺和肿瘤中环磷酰胺的生物测定法。
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