• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Studies on the mechanism of action of D-amino acid oxidase. Evidence for removal of substrate -hydrogen as a proton.

作者信息

Walsh C T, Schonbrunn A, Abeles R H

出版信息

J Biol Chem. 1971 Nov 25;246(22):6855-66.

PMID:4399475
Abstract
摘要

相似文献

1
Studies on the mechanism of action of D-amino acid oxidase. Evidence for removal of substrate -hydrogen as a proton.D-氨基酸氧化酶作用机制的研究。关于以质子形式去除底物氢的证据。
J Biol Chem. 1971 Nov 25;246(22):6855-66.
2
Studies on the elimination reaction of D-amino acid oxidase with -amino- -chlorobutyrate. Further evidence for abstraction of substrate -hydrogen as a proton.
J Biol Chem. 1973 Mar 25;248(6):1946-55.
3
On the reaction of D-amino acid oxidase with -chloroalanine.关于D-氨基酸氧化酶与β-氯丙氨酸的反应。
Z Naturforsch B Anorg Chem Org Chem Biochem Biophys Biol. 1972 Nov;27(11):1376-8. doi: 10.1515/znb-1972-1118.
4
D-amino acid oxidase. I. Spectrophotometric studies.
J Biol Chem. 1967 Sep 10;242(17):3957-62.
5
Location of hydrogen transfer steps in the mechanism of reduction of L-amino acid oxidase.
Biochem Biophys Res Commun. 1969 Jul 23;36(2):209-14. doi: 10.1016/0006-291x(69)90316-7.
6
Reaction mechanism of D-amino acid oxidase.
Adv Enzymol Relat Areas Mol Biol. 1971;34:41-78. doi: 10.1002/9780470122792.ch2.
7
Characteristics of the fluorescence spectra of apoenzyme and flavin portions of D-amino acid oxidase.D-氨基酸氧化酶的脱辅基酶蛋白和黄素部分的荧光光谱特征
Biochem Biophys Res Commun. 1970 Oct 23;41(2):381-5. doi: 10.1016/0006-291x(70)90515-2.
8
Mechanism of enzyme action. V. Demonstration of an initial step of enzyme-substrate complex using D-amino-acid oxidase and D-lactate or D-mandelate.
Biochim Biophys Acta. 1969 Jul 8;185(1):31-8. doi: 10.1016/0005-2744(69)90279-4.
9
On the interpretation of the absorption spectra of flavoproteins with special reference to D-amino acid oxidase.关于黄素蛋白吸收光谱的解释,特别提及D-氨基酸氧化酶。
Biochemistry. 1965 Jun;4(6):1161-73. doi: 10.1021/bi00882a027.
10
Substrate recognition and activation mechanism of D-amino acid oxidase: a study using substrate analogs.D-氨基酸氧化酶的底物识别与激活机制:一项使用底物类似物的研究
J Biochem. 2000 Aug;128(2):213-23. doi: 10.1093/oxfordjournals.jbchem.a022744.

引用本文的文献

1
MftD Catalyzes the Formation of a Biologically Active Redox Center in the Biosynthesis of the Ribosomally Synthesized and Post-translationally Modified Redox Cofactor Mycofactocin.MftD 催化了生物合成核糖体合成和翻译后修饰的氧化还原辅因子麦角硫因过程中生物活性氧化还原中心的形成。
J Am Chem Soc. 2019 Aug 28;141(34):13582-13591. doi: 10.1021/jacs.9b06102. Epub 2019 Aug 15.
2
Mechanistic Characterization of Escherichia coli l-Aspartate Oxidase from Kinetic Isotope Effects.基于动力学同位素效应的大肠杆菌L-天冬氨酸氧化酶的机制表征
Biochemistry. 2017 Aug 8;56(31):4044-4052. doi: 10.1021/acs.biochem.7b00307. Epub 2017 Jul 26.
3
Revisitation of the βCl-elimination reaction of D-amino acid oxidase: new interpretation of the reaction that sparked flavoprotein dehydrogenation mechanisms.
重新审视 D-氨基酸氧化酶的βCl-消除反应:引发黄素蛋白脱氢机制反应的新解释。
J Biol Chem. 2011 Nov 25;286(47):40987-98. doi: 10.1074/jbc.M111.266536. Epub 2011 Sep 23.
4
Catalysis at the intersection of biology, chemistry, and medicine.生物学、化学和医学交叉领域的催化作用。
J Biol Chem. 2010 Sep 24;285(39):29681-9. doi: 10.1074/jbc.X110.160309. Epub 2010 Jul 1.
5
Oxidation of amines by flavoproteins.黄素蛋白介导的胺类氧化。
Arch Biochem Biophys. 2010 Jan 1;493(1):13-25. doi: 10.1016/j.abb.2009.07.019. Epub 2009 Aug 3.
6
Biosynthesis of (-)-(1S,2R)-allocoronamic acyl thioester by an Fe(II)-dependent halogenase and a cyclopropane-forming flavoprotein.由铁(II)依赖性卤化酶和形成环丙烷的黄素蛋白生物合成(-)-(1S,2R)-别冠冕酰胺酰硫酯。
J Am Chem Soc. 2008 Oct 29;130(43):14022-3. doi: 10.1021/ja8064667. Epub 2008 Oct 2.
7
The 2.1 A structure of Aerococcus viridans L-lactate oxidase (LOX).绿色气球菌L-乳酸氧化酶(LOX)的2.1埃结构。
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt 12):1185-90. doi: 10.1107/S1744309106044678. Epub 2006 Nov 4.
8
Effect of glycidate, an inhibitor of glycolate synthesis in leaves, on the activity of some enzymes of the glycolate pathway.叶片中乙醇酸合成抑制剂乙醛酸酯对乙醇酸途径某些酶活性的影响。
Plant Physiol. 1978 Feb;61(2):236-41. doi: 10.1104/pp.61.2.236.
9
The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation.极高分辨率下D-氨基酸氧化酶的X射线结构揭示了黄素依赖性底物脱氢的化学机制。
Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12463-8. doi: 10.1073/pnas.97.23.12463.
10
NIH shift in flavin-dependent monooxygenation: mechanistic studies with 2-aminobenzoyl-CoA monooxygenase/reductase.美国国立卫生研究院黄素依赖性单加氧作用的转变:2-氨基苯甲酰辅酶A单加氧酶/还原酶的机制研究
Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):7831-6. doi: 10.1073/pnas.96.14.7831.